Abstract
Seven untreated patients with idiopathic generalized epilepsy were studied with recovery curve analysis using transcranial magnetic stimulation and compared with 16 controls. Patients had a shorter period of inhibition of the test response following a conditioning stimulus and demonstrated a period of increased facilitation of the test response at interstimulus intervals of 200 to 300 msec, which was similar to the mean interdischarge interval of spike-wave activity on EEG. This provides further evidence of cortical hyperexcitability in idiopathic generalized epilepsy.
Original language | English |
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Pages (from-to) | 1347-1349 |
Number of pages | 3 |
Journal | Neurology |
Volume | 53 |
Issue number | 6 |
DOIs | |
Publication status | Published - 12 Oct 1999 |
Externally published | Yes |
Keywords
- Cortical excitability
- Idiopathic generalized epilepsy
- Recovery curve analysis