Correlations between integrin {alphanubeta6} expression and clinico-pathological features in stage B and stage C rectal cancer

Seong Beom Ahn; Abidali Mohamedali; Charles Chan; Julie Fletcher; Sun Young Kwun; Candice Clarke; Owen F Dent; Pierre H Chapuis; Edouard C Nice; Mark S Baker

doi:10.1371/journal.pone.0097248

Correlations between integrin {alphanubeta6} expression and clinico-pathological features in stage B and stage C rectal cancer

Seong Beom Ahn, Abidali Mohamedali, Charles Chan, Julie Fletcher, Sun Young Kwun, Candice Clarke, Owen F Dent, Pierre H Chapuis, Edouard C Nice, Mark S Baker

Biochemistry & Molecular Biology

Research output: Contribution to journal › Article › Research › peer-review

9 Citations (Scopus)

Abstract

Integrin alphanubeta6 is highly expressed in a range of human cancers and frequently correlates with patient survival. This study examines correlations between alphanubeta6 expression and patient clinico-pathological features in Stage B and Stage C rectal cancer, including overall survival. Expression of alphanubeta6 was measured in 362 Stage B or C rectal cancer tissue samples at the tumour central region, invasive tumour front and adjacent non-neoplastic mucosa using immunohistochemistry. Distribution of alphanubeta6 was found to be significantly higher at the invasive front compared to central regions of the tumour (p

Original language	English
Pages (from-to)	1 - 8
Number of pages	8
Journal	PLoS ONE
Volume	9
Issue number	5 (Art. ID: e97248)
DOIs	https://doi.org/10.1371/journal.pone.0097248
Publication status	Published - 2014

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10.1371/journal.pone.0097248

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Ahn, Seong Beom ; Mohamedali, Abidali ; Chan, Charles ; Fletcher, Julie ; Kwun, Sun Young ; Clarke, Candice ; Dent, Owen F ; Chapuis, Pierre H ; Nice, Edouard C ; Baker, Mark S. / Correlations between integrin {alphanubeta6} expression and clinico-pathological features in stage B and stage C rectal cancer. In: PLoS ONE. 2014 ; Vol. 9, No. 5 (Art. ID: e97248). pp. 1 - 8.

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Correlations between integrin {alphanubeta6} expression and clinico-pathological features in stage B and stage C rectal cancer. / Ahn, Seong Beom; Mohamedali, Abidali; Chan, Charles; Fletcher, Julie; Kwun, Sun Young; Clarke, Candice; Dent, Owen F; Chapuis, Pierre H; Nice, Edouard C; Baker, Mark S.

In: PLoS ONE, Vol. 9, No. 5 (Art. ID: e97248), 2014, p. 1 - 8.

Research output: Contribution to journal › Article › Research › peer-review

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AU - Ahn, Seong Beom

AU - Mohamedali, Abidali

AU - Chan, Charles

AU - Fletcher, Julie

AU - Kwun, Sun Young

AU - Clarke, Candice

AU - Dent, Owen F

AU - Chapuis, Pierre H

AU - Nice, Edouard C

AU - Baker, Mark S

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AB - Integrin alphanubeta6 is highly expressed in a range of human cancers and frequently correlates with patient survival. This study examines correlations between alphanubeta6 expression and patient clinico-pathological features in Stage B and Stage C rectal cancer, including overall survival. Expression of alphanubeta6 was measured in 362 Stage B or C rectal cancer tissue samples at the tumour central region, invasive tumour front and adjacent non-neoplastic mucosa using immunohistochemistry. Distribution of alphanubeta6 was found to be significantly higher at the invasive front compared to central regions of the tumour (p

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Correlations between integrin {alphanubeta6} expression and clinico-pathological features in stage B and stage C rectal cancer

Abstract

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Colorectal Cancer Membrane Protein Interactomics (A Major Discriminator of Clinical Outcome)

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Correlations between integrin {alphanubeta6} expression and clinico-pathological features in stage B and stage C rectal cancer

Abstract

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Colorectal Cancer Membrane Protein Interactomics (A Major Discriminator of Clinical Outcome)

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