TY - JOUR
T1 - Correlation of patient-reported outcome measures to performance-based function in critical care survivors
T2 - PREDICTABLE
AU - Paton, Michelle
AU - Lane, Rebecca
AU - Paul, Eldho
AU - Linke, Natalie
AU - Shehabi, Yahya
AU - Hodgson, Carol L.
N1 - Funding Information:
No funding was obtained for this publication. The PREDICT study received an NHMRC grant which aided in patient-reported outcome data collection. Carol Hodgson was supported by a Heart Foundation Future Fellowship and an NHMRC Investigator Grant.
Funding Information:
The authors would like to thank the work of the PREDICT Management Committee (Hodgson CL, Bailey M, Barrett J, Bellomo R, Cooper J, Gabbe BJ, Higgins AM, Linke N, Myles PS, Paton M, Philpot S, Shulman M, and Young M).
Publisher Copyright:
© 2022 Australian College of Critical Care Nurses Ltd
PY - 2023/7
Y1 - 2023/7
N2 - Background: Establishing sequela following critical illness is a public health priority; however, recruitment and retention of this cohort make assessing functional outcomes difficult. Completing patient-reported outcome measures (PROMs) via telephone may improve participant and researcher involvement; however, there is little evidence regarding the correlation of PROMs to performance-based outcome measures in critical care survivors. Objectives: The objective of this study was to assess the relationship between self-reported and performance-based measures of function in survivors of critical illness. Methods: This was a nested cohort study of patients enrolled within a previously published study determining predictors of disability-free survival. Spearman's correlation (rs) was calculated between four performance-based outcomes (the Functional Independence Measure [FIM], 6-min walk distance [6MWD], Functional Reach Test [FRT], and grip strength) that were collected during a home visit 6 months following their intensive care unit admission, with two commonly used PROMs (World Health Organization Disability Assessment Scale 2.0 12 Level [WHODAS 2.0] and EuroQol-5 Dimension-5 Level [EQ-5D-5L]) obtained via phone interview (via the PREDICT study) at the same time point. Results: There were 38 PROMs obtained from 40 recruited patients (mean age = 59.8 ± 16 yrs, M:F = 24:16). All 40 completed the FIM and grip strength, 37 the 6MWD, and 39 the FRT. A strong correlation was found between the primary outcome of the WHODAS 2.0 with all performance-based outcomes apart from grip strength where a moderate correlation was identified. Although strong correlations were also established between the EQ-5D-5L utility score and the FIM, 6MWD, and FRT, it only correlated weakly with grip strength. The EQ-5D overall global health rating only had very weak to moderate correlations with the performance-based outcomes. Conclusion: The WHODAS 2.0 correlated stronger across multiple performance-based outcome measures of functional recovery and is recommended for use in survivors of critical illness.
AB - Background: Establishing sequela following critical illness is a public health priority; however, recruitment and retention of this cohort make assessing functional outcomes difficult. Completing patient-reported outcome measures (PROMs) via telephone may improve participant and researcher involvement; however, there is little evidence regarding the correlation of PROMs to performance-based outcome measures in critical care survivors. Objectives: The objective of this study was to assess the relationship between self-reported and performance-based measures of function in survivors of critical illness. Methods: This was a nested cohort study of patients enrolled within a previously published study determining predictors of disability-free survival. Spearman's correlation (rs) was calculated between four performance-based outcomes (the Functional Independence Measure [FIM], 6-min walk distance [6MWD], Functional Reach Test [FRT], and grip strength) that were collected during a home visit 6 months following their intensive care unit admission, with two commonly used PROMs (World Health Organization Disability Assessment Scale 2.0 12 Level [WHODAS 2.0] and EuroQol-5 Dimension-5 Level [EQ-5D-5L]) obtained via phone interview (via the PREDICT study) at the same time point. Results: There were 38 PROMs obtained from 40 recruited patients (mean age = 59.8 ± 16 yrs, M:F = 24:16). All 40 completed the FIM and grip strength, 37 the 6MWD, and 39 the FRT. A strong correlation was found between the primary outcome of the WHODAS 2.0 with all performance-based outcomes apart from grip strength where a moderate correlation was identified. Although strong correlations were also established between the EQ-5D-5L utility score and the FIM, 6MWD, and FRT, it only correlated weakly with grip strength. The EQ-5D overall global health rating only had very weak to moderate correlations with the performance-based outcomes. Conclusion: The WHODAS 2.0 correlated stronger across multiple performance-based outcome measures of functional recovery and is recommended for use in survivors of critical illness.
KW - Critical care
KW - Critical care outcomes
KW - Intensive care units
KW - Physical functional performance
KW - Physical therapy modalities
UR - http://www.scopus.com/inward/record.url?scp=85133842387&partnerID=8YFLogxK
U2 - 10.1016/j.aucc.2022.05.006
DO - 10.1016/j.aucc.2022.05.006
M3 - Article
C2 - 35810078
AN - SCOPUS:85133842387
SN - 1036-7314
VL - 36
SP - 485
EP - 491
JO - Australian Critical Care
JF - Australian Critical Care
IS - 4
ER -
