Correlation of Anterior Interbody Graft Choice with Patient-Reported Outcomes in Cervical Spine Trauma

Hui Qing Lee, Chien Yew Kow, Jay Shen Ng, Patrick Chan, Lu Ton, Greg Etherington, Susan Liew, Martin Hunn, Mark Fitzgerald, Jin Wee Tee

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Study Design:
Ambispective observational cohort study.
Objectives:
Synthetic graft usage avoids morbidity associated with harvest and reduces operative time. This study aims to evaluate outcomes of anterior cervical stabilization surgery using a synthetic cage in comparison with iliac crest bone graft (ICBG) following cervical spine trauma.
Methods:
An ambispective review was conducted on patients from the Alfred Trauma Registry. Consecutive patients treated at a level 1 trauma center, aged 18 years and older who were treated with standalone anterior cervical stabilization following spine trauma (2011-2016) were included in the study. Primary outcome measures were patient overall satisfaction, Neck Disability Index (NDI), neck pain 10-point visual analogue scale (VAS-neck) and arm pain 10-point visual analogue scale (VAS-arm). Secondary outcome measures were radiographic evidence of fusion and rate of revision surgery. All patients had follow-up for at least 1 year.
Results:
Between 2011 and 2016, 114 traumatic disc levels in 104 patients were treated. ICBG was used in 32% and polyetheretherketone (PEEK) cage in 68% of the patients. Both groups had similar demographic metrics. There was no significant difference in primary outcome measures between the graft types: (1) patient satisfaction (P = .15), (2) NDI (P = .11), (3) VAS-neck (P = .13), and (4) VAS-arm (P = .20). Radiology based fusion assessment 6 months postsurgery did not show statistical significance (P = .10). The rates of revision surgery were similar.
Conclusions:
This study showed no significant difference in patient-reported outcome measures when comparing the usage of PEEK cage and ICBG in anterior stand alone cervical spine stabilization. Level 1 evidence studies are required to further investigate this finding.
Original languageEnglish
Number of pages8
JournalGlobal Spine Journal
DOIs
Publication statusAccepted/In press - Jan 2019
Externally publishedYes

Cite this

@article{748052afac9f4928955a62563e626dbd,
title = "Correlation of Anterior Interbody Graft Choice with Patient-Reported Outcomes in Cervical Spine Trauma",
abstract = "Study Design:Ambispective observational cohort study.Objectives:Synthetic graft usage avoids morbidity associated with harvest and reduces operative time. This study aims to evaluate outcomes of anterior cervical stabilization surgery using a synthetic cage in comparison with iliac crest bone graft (ICBG) following cervical spine trauma.Methods:An ambispective review was conducted on patients from the Alfred Trauma Registry. Consecutive patients treated at a level 1 trauma center, aged 18 years and older who were treated with standalone anterior cervical stabilization following spine trauma (2011-2016) were included in the study. Primary outcome measures were patient overall satisfaction, Neck Disability Index (NDI), neck pain 10-point visual analogue scale (VAS-neck) and arm pain 10-point visual analogue scale (VAS-arm). Secondary outcome measures were radiographic evidence of fusion and rate of revision surgery. All patients had follow-up for at least 1 year.Results:Between 2011 and 2016, 114 traumatic disc levels in 104 patients were treated. ICBG was used in 32{\%} and polyetheretherketone (PEEK) cage in 68{\%} of the patients. Both groups had similar demographic metrics. There was no significant difference in primary outcome measures between the graft types: (1) patient satisfaction (P = .15), (2) NDI (P = .11), (3) VAS-neck (P = .13), and (4) VAS-arm (P = .20). Radiology based fusion assessment 6 months postsurgery did not show statistical significance (P = .10). The rates of revision surgery were similar.Conclusions:This study showed no significant difference in patient-reported outcome measures when comparing the usage of PEEK cage and ICBG in anterior stand alone cervical spine stabilization. Level 1 evidence studies are required to further investigate this finding.",
author = "Lee, {Hui Qing} and Kow, {Chien Yew} and Ng, {Jay Shen} and Patrick Chan and Lu Ton and Greg Etherington and Susan Liew and Martin Hunn and Mark Fitzgerald and Tee, {Jin Wee}",
year = "2019",
month = "1",
doi = "10.1177/2192568219828720",
language = "English",
journal = "Global Spine Journal",
issn = "2192-5682",
publisher = "Thieme Publishing",

}

Correlation of Anterior Interbody Graft Choice with Patient-Reported Outcomes in Cervical Spine Trauma. / Lee, Hui Qing; Kow, Chien Yew; Ng, Jay Shen; Chan, Patrick; Ton, Lu; Etherington, Greg; Liew, Susan; Hunn, Martin; Fitzgerald, Mark; Tee, Jin Wee.

In: Global Spine Journal, 01.2019.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Correlation of Anterior Interbody Graft Choice with Patient-Reported Outcomes in Cervical Spine Trauma

AU - Lee, Hui Qing

AU - Kow, Chien Yew

AU - Ng, Jay Shen

AU - Chan, Patrick

AU - Ton, Lu

AU - Etherington, Greg

AU - Liew, Susan

AU - Hunn, Martin

AU - Fitzgerald, Mark

AU - Tee, Jin Wee

PY - 2019/1

Y1 - 2019/1

N2 - Study Design:Ambispective observational cohort study.Objectives:Synthetic graft usage avoids morbidity associated with harvest and reduces operative time. This study aims to evaluate outcomes of anterior cervical stabilization surgery using a synthetic cage in comparison with iliac crest bone graft (ICBG) following cervical spine trauma.Methods:An ambispective review was conducted on patients from the Alfred Trauma Registry. Consecutive patients treated at a level 1 trauma center, aged 18 years and older who were treated with standalone anterior cervical stabilization following spine trauma (2011-2016) were included in the study. Primary outcome measures were patient overall satisfaction, Neck Disability Index (NDI), neck pain 10-point visual analogue scale (VAS-neck) and arm pain 10-point visual analogue scale (VAS-arm). Secondary outcome measures were radiographic evidence of fusion and rate of revision surgery. All patients had follow-up for at least 1 year.Results:Between 2011 and 2016, 114 traumatic disc levels in 104 patients were treated. ICBG was used in 32% and polyetheretherketone (PEEK) cage in 68% of the patients. Both groups had similar demographic metrics. There was no significant difference in primary outcome measures between the graft types: (1) patient satisfaction (P = .15), (2) NDI (P = .11), (3) VAS-neck (P = .13), and (4) VAS-arm (P = .20). Radiology based fusion assessment 6 months postsurgery did not show statistical significance (P = .10). The rates of revision surgery were similar.Conclusions:This study showed no significant difference in patient-reported outcome measures when comparing the usage of PEEK cage and ICBG in anterior stand alone cervical spine stabilization. Level 1 evidence studies are required to further investigate this finding.

AB - Study Design:Ambispective observational cohort study.Objectives:Synthetic graft usage avoids morbidity associated with harvest and reduces operative time. This study aims to evaluate outcomes of anterior cervical stabilization surgery using a synthetic cage in comparison with iliac crest bone graft (ICBG) following cervical spine trauma.Methods:An ambispective review was conducted on patients from the Alfred Trauma Registry. Consecutive patients treated at a level 1 trauma center, aged 18 years and older who were treated with standalone anterior cervical stabilization following spine trauma (2011-2016) were included in the study. Primary outcome measures were patient overall satisfaction, Neck Disability Index (NDI), neck pain 10-point visual analogue scale (VAS-neck) and arm pain 10-point visual analogue scale (VAS-arm). Secondary outcome measures were radiographic evidence of fusion and rate of revision surgery. All patients had follow-up for at least 1 year.Results:Between 2011 and 2016, 114 traumatic disc levels in 104 patients were treated. ICBG was used in 32% and polyetheretherketone (PEEK) cage in 68% of the patients. Both groups had similar demographic metrics. There was no significant difference in primary outcome measures between the graft types: (1) patient satisfaction (P = .15), (2) NDI (P = .11), (3) VAS-neck (P = .13), and (4) VAS-arm (P = .20). Radiology based fusion assessment 6 months postsurgery did not show statistical significance (P = .10). The rates of revision surgery were similar.Conclusions:This study showed no significant difference in patient-reported outcome measures when comparing the usage of PEEK cage and ICBG in anterior stand alone cervical spine stabilization. Level 1 evidence studies are required to further investigate this finding.

U2 - 10.1177/2192568219828720

DO - 10.1177/2192568219828720

M3 - Article

JO - Global Spine Journal

JF - Global Spine Journal

SN - 2192-5682

ER -