Corpus callosum size and shape in individuals with current and past depression

Mark Walterfang, Murat Yucel, Sarah Barton, David Reutens, Amanda Gabrielle Wood, Jian Chen, Valentina Lorenzetti, Dennis Velakoulis, Christos Pantelis, Nicholas B Allen

Research output: Contribution to journalArticleResearchpeer-review

33 Citations (Scopus)

Abstract

Corpus callosum size and shape in individuals with current and past depression. BACKGROUND: The corpus callosum enables the efficient linking of the two cerebral hemispheres. Reductions in the size of the anterior callosum have been described in geriatric depression, although findings in young adults have been much more equivocal. METHODS: Data was acquired in 26 currently depressed (mean age 32.15 years, 5/26 male) and 28 remitted non-geriatric adults (mean age 36.36 years, 7/28 male), and 32 control subjects (mean age 34.41 years, 11/32 male). The total area, length and curvature of the callosum, and regional thickness along 39 points, from a mid-sagittal T1-weighted magnetic resonance image were compared across the groups. RESULTS: Total area, length and curvature did not differ between the groups.
Original languageEnglish
Pages (from-to)411 - 420
Number of pages10
JournalJournal of Affective Disorders
Volume115
Issue number3
Publication statusPublished - 2009

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