Corpus callosum size and shape in first-episode affective and schizophrenia-spectrum psychosis

Mark Walterfang, Amanda Gabrielle Wood, David Reutens, Stephen J Wood, Jian Chen, Dennis Velakoulis, Patrick D McGorry, Christos Pantelis

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45 Citations (Scopus)

Abstract

Corpus callosum size and shape in first-episode affective and schizophrenia-spectrum psychosis. Reductions in the size of the anterior callosum have been described for both first-episode and established schizophrenia and bipolar affective disorder, but never in individuals with psychotic bipolar disorder. We recruited 110 first-episode psychosis subjects (74 schizophrenia spectrum and 36 affective psychosis) and 36 age- and gender-matched controls. The callosum was extracted from a mid-sagittal slice from T1-weighted magnetic resonance images, and total area, length and curvature of the callosum were compared.
Original languageEnglish
Pages (from-to)77 - 82
Number of pages6
JournalPsychiatry Research
Volume173
Issue number1
Publication statusPublished - 2009

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