Copper-mediated controlled radical polymerization under biological conditions: SET-LRP in blood serum

Qiang Zhang, Zaidong Li, Paul Wilson, David M. Haddleton

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Abstract

The polymerization of hydrophilic monomers is reported utilizing Cu(0)-mediated living radical polymerization, SET-LRP. Highly active Cu(0) is formed in situ as a result of rapid disproportionation of [Cu(i)(Me 6-Tren)Br] in serum. Disproportionation and homogenous controlled radical polymerization (PDI 1.09-1.25) are performed for the first time in blood (sheep) serum.

Original languageEnglish
Pages (from-to)6608-6610
Number of pages3
JournalChemical Communications
Volume49
Issue number59
DOIs
Publication statusPublished - 28 Jul 2013
Externally publishedYes

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