Controlled release strategies in tissue engineering

Jeffrey J. Rice; Mikaël M. Martino; Evan A. Scott; Jeffrey A. Hubbell

doi:10.1016/B978-0-12-420145-3.00011-0

Controlled release strategies in tissue engineering

Jeffrey J. Rice, Mikaël M. Martino, Evan A. Scott, Jeffrey A. Hubbell

Research output: Chapter in Book/Report/Conference proceeding › Chapter (Book) › Other › peer-review

3 Citations (Scopus)

Abstract

The controlled release of biological factors is an essential component of the many aspects of tissue engineering. The primary objective of the controlled release of cell signaling molecules is to present desired biological factors to the targeted cells at an optimal concentration for an optimal duration of time. Over the previous decades, engineers have designed a variety of systems to precisely control the release rates of various biomolecules for many tissue engineering applications. This chapter describes the prominent methods that have been used to entrap bioactive factors within biomaterials to control the presentation and delivery of these factors.

Original language	English
Title of host publication	Tissue Engineering
Subtitle of host publication	Second Edition
Editors	Clemens A. van Blitterswijk, Jan de Boer
Place of Publication	London UK
Publisher	Academic Press
Pages	347-392
Number of pages	46
ISBN (Print)	9780124201453
DOIs	https://doi.org/10.1016/B978-0-12-420145-3.00011-0
Publication status	Published - 2014
Externally published	Yes

Keywords

Biomaterials
Controlled release
Extracellular matrix
Growth factors
Hydrogels

Access to Document

10.1016/B978-0-12-420145-3.00011-0

Cite this

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title = "Controlled release strategies in tissue engineering",

abstract = "The controlled release of biological factors is an essential component of the many aspects of tissue engineering. The primary objective of the controlled release of cell signaling molecules is to present desired biological factors to the targeted cells at an optimal concentration for an optimal duration of time. Over the previous decades, engineers have designed a variety of systems to precisely control the release rates of various biomolecules for many tissue engineering applications. This chapter describes the prominent methods that have been used to entrap bioactive factors within biomaterials to control the presentation and delivery of these factors.",

keywords = "Biomaterials, Controlled release, Extracellular matrix, Growth factors, Hydrogels",

author = "Rice, {Jeffrey J.} and Martino, {Mika{\"e}l M.} and Scott, {Evan A.} and Hubbell, {Jeffrey A.}",

year = "2014",

doi = "10.1016/B978-0-12-420145-3.00011-0",

language = "English",

isbn = "9780124201453",

pages = "347--392",

editor = "{van Blitterswijk}, {Clemens A.} and {de Boer}, Jan",

booktitle = "Tissue Engineering",

publisher = "Academic Press",

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TY - CHAP

T1 - Controlled release strategies in tissue engineering

AU - Rice, Jeffrey J.

AU - Martino, Mikaël M.

AU - Scott, Evan A.

AU - Hubbell, Jeffrey A.

PY - 2014

Y1 - 2014

N2 - The controlled release of biological factors is an essential component of the many aspects of tissue engineering. The primary objective of the controlled release of cell signaling molecules is to present desired biological factors to the targeted cells at an optimal concentration for an optimal duration of time. Over the previous decades, engineers have designed a variety of systems to precisely control the release rates of various biomolecules for many tissue engineering applications. This chapter describes the prominent methods that have been used to entrap bioactive factors within biomaterials to control the presentation and delivery of these factors.

AB - The controlled release of biological factors is an essential component of the many aspects of tissue engineering. The primary objective of the controlled release of cell signaling molecules is to present desired biological factors to the targeted cells at an optimal concentration for an optimal duration of time. Over the previous decades, engineers have designed a variety of systems to precisely control the release rates of various biomolecules for many tissue engineering applications. This chapter describes the prominent methods that have been used to entrap bioactive factors within biomaterials to control the presentation and delivery of these factors.

KW - Biomaterials

KW - Controlled release

KW - Extracellular matrix

KW - Growth factors

KW - Hydrogels

UR - http://www.scopus.com/inward/record.url?scp=84967335390&partnerID=8YFLogxK

U2 - 10.1016/B978-0-12-420145-3.00011-0

DO - 10.1016/B978-0-12-420145-3.00011-0

M3 - Chapter (Book)

AN - SCOPUS:84967335390

SN - 9780124201453

SP - 347

EP - 392

BT - Tissue Engineering

A2 - van Blitterswijk, Clemens A.

A2 - de Boer, Jan

PB - Academic Press

CY - London UK

ER -

Controlled release strategies in tissue engineering

Abstract

Keywords

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Research output

Controlled release strategies in tissue engineering

Cite this