Contribution of the COMT Val158Met variant to symptomatic knee osteoarthritis

Tuhina Neogi, Anushka Soni, Sally A Doherty, Laura Louise Laslett, Rose A Maciewicz, Deborah J Hart, Weiya Zhang, Kenneth R Muir, Margaret Wheeler, Cyrus Cooper, Timothy D Spector, Flavia Maria Cicuttini, Graeme Jones, Michael C Nevitt, Y Liu, Nigel K Arden, Michael Doherty, Ana Maria Valdes

Research output: Contribution to journalLetterResearchpeer-review

12 Citations (Scopus)

Abstract

We assessed whether the Met allele in the COMT gene is involved in increased risk of symptomatic knee OA in seven cohorts: five cohorts from the UK, one from Australia and two from the USA were included (table 1). Assembly of the cohorts was approved by the local research ethics committees and all study participants gave fully informed consent to participate in genetic studies.
Original languageEnglish
Pages (from-to)315 - 317
Number of pages3
JournalAnnals of the Rheumatic Diseases
Volume73
Issue number1
DOIs
Publication statusPublished - 2014

Cite this

Neogi, T., Soni, A., Doherty, S. A., Laslett, L. L., Maciewicz, R. A., Hart, D. J., ... Valdes, A. M. (2014). Contribution of the COMT Val158Met variant to symptomatic knee osteoarthritis. Annals of the Rheumatic Diseases, 73(1), 315 - 317. https://doi.org/10.1136/annrheumdis-2013-203836
Neogi, Tuhina ; Soni, Anushka ; Doherty, Sally A ; Laslett, Laura Louise ; Maciewicz, Rose A ; Hart, Deborah J ; Zhang, Weiya ; Muir, Kenneth R ; Wheeler, Margaret ; Cooper, Cyrus ; Spector, Timothy D ; Cicuttini, Flavia Maria ; Jones, Graeme ; Nevitt, Michael C ; Liu, Y ; Arden, Nigel K ; Doherty, Michael ; Valdes, Ana Maria. / Contribution of the COMT Val158Met variant to symptomatic knee osteoarthritis. In: Annals of the Rheumatic Diseases. 2014 ; Vol. 73, No. 1. pp. 315 - 317.
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abstract = "We assessed whether the Met allele in the COMT gene is involved in increased risk of symptomatic knee OA in seven cohorts: five cohorts from the UK, one from Australia and two from the USA were included (table 1). Assembly of the cohorts was approved by the local research ethics committees and all study participants gave fully informed consent to participate in genetic studies.",
author = "Tuhina Neogi and Anushka Soni and Doherty, {Sally A} and Laslett, {Laura Louise} and Maciewicz, {Rose A} and Hart, {Deborah J} and Weiya Zhang and Muir, {Kenneth R} and Margaret Wheeler and Cyrus Cooper and Spector, {Timothy D} and Cicuttini, {Flavia Maria} and Graeme Jones and Nevitt, {Michael C} and Y Liu and Arden, {Nigel K} and Michael Doherty and Valdes, {Ana Maria}",
year = "2014",
doi = "10.1136/annrheumdis-2013-203836",
language = "English",
volume = "73",
pages = "315 -- 317",
journal = "Annals of the Rheumatic Diseases",
issn = "0003-4967",
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Neogi, T, Soni, A, Doherty, SA, Laslett, LL, Maciewicz, RA, Hart, DJ, Zhang, W, Muir, KR, Wheeler, M, Cooper, C, Spector, TD, Cicuttini, FM, Jones, G, Nevitt, MC, Liu, Y, Arden, NK, Doherty, M & Valdes, AM 2014, 'Contribution of the COMT Val158Met variant to symptomatic knee osteoarthritis', Annals of the Rheumatic Diseases, vol. 73, no. 1, pp. 315 - 317. https://doi.org/10.1136/annrheumdis-2013-203836

Contribution of the COMT Val158Met variant to symptomatic knee osteoarthritis. / Neogi, Tuhina; Soni, Anushka; Doherty, Sally A; Laslett, Laura Louise; Maciewicz, Rose A; Hart, Deborah J; Zhang, Weiya; Muir, Kenneth R; Wheeler, Margaret; Cooper, Cyrus; Spector, Timothy D; Cicuttini, Flavia Maria; Jones, Graeme; Nevitt, Michael C; Liu, Y; Arden, Nigel K; Doherty, Michael; Valdes, Ana Maria.

In: Annals of the Rheumatic Diseases, Vol. 73, No. 1, 2014, p. 315 - 317.

Research output: Contribution to journalLetterResearchpeer-review

TY - JOUR

T1 - Contribution of the COMT Val158Met variant to symptomatic knee osteoarthritis

AU - Neogi, Tuhina

AU - Soni, Anushka

AU - Doherty, Sally A

AU - Laslett, Laura Louise

AU - Maciewicz, Rose A

AU - Hart, Deborah J

AU - Zhang, Weiya

AU - Muir, Kenneth R

AU - Wheeler, Margaret

AU - Cooper, Cyrus

AU - Spector, Timothy D

AU - Cicuttini, Flavia Maria

AU - Jones, Graeme

AU - Nevitt, Michael C

AU - Liu, Y

AU - Arden, Nigel K

AU - Doherty, Michael

AU - Valdes, Ana Maria

PY - 2014

Y1 - 2014

N2 - We assessed whether the Met allele in the COMT gene is involved in increased risk of symptomatic knee OA in seven cohorts: five cohorts from the UK, one from Australia and two from the USA were included (table 1). Assembly of the cohorts was approved by the local research ethics committees and all study participants gave fully informed consent to participate in genetic studies.

AB - We assessed whether the Met allele in the COMT gene is involved in increased risk of symptomatic knee OA in seven cohorts: five cohorts from the UK, one from Australia and two from the USA were included (table 1). Assembly of the cohorts was approved by the local research ethics committees and all study participants gave fully informed consent to participate in genetic studies.

UR - http://ard.bmj.com/content/73/1/315.long

U2 - 10.1136/annrheumdis-2013-203836

DO - 10.1136/annrheumdis-2013-203836

M3 - Letter

VL - 73

SP - 315

EP - 317

JO - Annals of the Rheumatic Diseases

JF - Annals of the Rheumatic Diseases

SN - 0003-4967

IS - 1

ER -