Abstract
The concentration of plasma interleukin-6 (IL-6) increases during physical exercise, but until recently the cellular origin of this increase has been unknown. Recent work has identified that skeletal muscle is a major source of this increase and the release of IL-6 from muscle can mediate metabolic processes. IL-6 is, therefore, the first identified "myokine" released from muscle that can now be termed an endocrine organ.
Original language | English |
---|---|
Pages (from-to) | 114-119 |
Number of pages | 6 |
Journal | Exercise and Sport Sciences Reviews |
Volume | 33 |
Issue number | 3 |
DOIs | |
Publication status | Published - 1 Jul 2005 |
Externally published | Yes |
Keywords
- Cytokines
- Hepatic glucose production
- Interleukin-6
- Lipolysis
- Metabolic processes