TY - JOUR
T1 - Continuously tunable ion rectification and conductance in submicrochannels stemming from thermoresponsive polymer self-assembly
AU - Wu, Yafeng
AU - Yang, Guang
AU - Lin, Mingchang
AU - Kong, Xiangyu
AU - Mi, Li
AU - Liu, Songqin
AU - Chen, Guosong
AU - Tian, Ye
AU - Jiang, Lei
PY - 2019/9/2
Y1 - 2019/9/2
N2 - A biomimetic conical submicrochannel (tip side ca. 400 nm) with functions of continuously tunable ion rectification and conductance based on thermoresponsive polymer layer-by-layer (LbL) self-assembly is presented. These self-assembled polymers with different layers exhibited a capability to regulate the effective channel diameter, and different ion rectifications/conductance were achieved. By controlling temperature, the conformation and wettability of the assembled polymers were reversibly transformed, thus the ion rectification/conductance could be further adjusted subtly. Owing to the synergistic effect, the ion conductance could be tuned over a wide range spanning three orders of magnitude. Moreover, the proposed system can be applied for on-demand on-off molecule delivery, which was important for disease therapy. This study opens a new door for regulating channel size according to actual demand and sensing big targets with different size with one channel.
AB - A biomimetic conical submicrochannel (tip side ca. 400 nm) with functions of continuously tunable ion rectification and conductance based on thermoresponsive polymer layer-by-layer (LbL) self-assembly is presented. These self-assembled polymers with different layers exhibited a capability to regulate the effective channel diameter, and different ion rectifications/conductance were achieved. By controlling temperature, the conformation and wettability of the assembled polymers were reversibly transformed, thus the ion rectification/conductance could be further adjusted subtly. Owing to the synergistic effect, the ion conductance could be tuned over a wide range spanning three orders of magnitude. Moreover, the proposed system can be applied for on-demand on-off molecule delivery, which was important for disease therapy. This study opens a new door for regulating channel size according to actual demand and sensing big targets with different size with one channel.
KW - self-assembly
KW - submicrochannels
KW - thermoresponsive polymers
KW - tunable ion conductance
KW - tunable ion rectification
UR - http://www.scopus.com/inward/record.url?scp=85070095386&partnerID=8YFLogxK
U2 - 10.1002/anie.201906360
DO - 10.1002/anie.201906360
M3 - Article
AN - SCOPUS:85070095386
SN - 1433-7851
VL - 58
SP - 12481
EP - 12485
JO - Angewandte Chemie - International Edition
JF - Angewandte Chemie - International Edition
IS - 36
ER -