TY - JOUR
T1 - Continuous hemofiltration for anasarca
T2 - Recovery of renal function after 71 liters of net ultrafiltration
AU - Prowle, J.
AU - Bellomo, Rinaldo
AU - Buckmaster, J.
AU - Gutteridge, G.
AU - Hart, G.
AU - Opdam, H.
AU - Silvester, W.
AU - Warrillow, S.
PY - 2008/1/1
Y1 - 2008/1/1
N2 - We report on a 64-year-old female presenting with anasarca secondary to volume loading in the setting of chronic liver disease, acute on chronic renal failure, circulatory failure and sepsis. Over 37 days, a net negative fluid balance of 71 L was achieved using continuous hemofiltration, with spontaneous recovery of urine output, vasopressor independence and resolution of coagulopathy. This case report underlines the pathophysiological role of tissue edema in the downward spiral of hepato-renal and cardio-renal dysfunction and illustrates that very large volumes of tissue fluid can be safely and effectively removed with continuous renal replacement therapy, thereby permitting recovery of organ function. To our knowledge, there have been no previous reports of such large volume net fluid removal by progressive ultrafiltration in the intensive care unit.
AB - We report on a 64-year-old female presenting with anasarca secondary to volume loading in the setting of chronic liver disease, acute on chronic renal failure, circulatory failure and sepsis. Over 37 days, a net negative fluid balance of 71 L was achieved using continuous hemofiltration, with spontaneous recovery of urine output, vasopressor independence and resolution of coagulopathy. This case report underlines the pathophysiological role of tissue edema in the downward spiral of hepato-renal and cardio-renal dysfunction and illustrates that very large volumes of tissue fluid can be safely and effectively removed with continuous renal replacement therapy, thereby permitting recovery of organ function. To our knowledge, there have been no previous reports of such large volume net fluid removal by progressive ultrafiltration in the intensive care unit.
KW - Acute kidney failure
KW - Congestive heart failure
KW - Edema
KW - Hemofiltration
KW - Hepatorenal syndrome
KW - Liver cirrhosis
KW - Ultrafiltration
UR - http://www.scopus.com/inward/record.url?scp=45949088108&partnerID=8YFLogxK
U2 - 10.1177/039139880803100415
DO - 10.1177/039139880803100415
M3 - Article
C2 - 18432595
AN - SCOPUS:45949088108
VL - 31
SP - 367
EP - 370
JO - International Journal of Artificial Organs
JF - International Journal of Artificial Organs
SN - 0391-3988
IS - 4
ER -