Consultation and treatment behaviour of infertile couples in China: a population-based study

Danni Zheng, Zehong Zhou, Rong Li, Hongping Wu, Suxin Xu, Yuefan Kang, Yunxia Cao, Xiujuan Chen, Yimin Zhu, Shuguang Xu, Zi Jiang Chen, Ben Willem Mol, Jie Qiao

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Research question: The prevalence of infertility in couples actively trying to conceive is 25%. What is the consultation-seeking behaviour, diagnosis and related treatment in infertile couples across China? Design: Large cross-sectional population-based study in 2010–2011, in which 25,270 couples from eight provinces/municipalities in China were approached by a multistage stratified cluster sampling strategy. Results: Among the 2680 couples reporting infertility, 1246 infertile couples consulted a fertility doctor. Age of the couple, man's body mass index and women's educational level were found to be associated with consultation behaviour. After the fertility work-up, diagnoses were tubal infertility (n = 353, 28.3%), unexplained infertility (n = 311, 25.0%), male infertility (n = 234, 18.8%), ovulatory disorder (n = 194, 15.6%) and endometriosis (n = 34, 2.7%), while 8.6% (n = 107) were not classified. Most couples received non-assisted reproductive technology (ART) fertility treatment (n = 906, 89.3%), with a proportion using traditional Chinese medicine (TCM) (n = 298, 29.4%). Intrauterine insemination (n = 62, 6.1%) and IVF/intracytoplasmic sperm injection (n = 57, 5.6%) were less frequent. Medical treatment and outcomes among five subtypes of infertility were also reported: about 30% of couples with unexplained infertility (n = 94, 30.3%) or male infertility (n = 67, 29.0%) used TCM to treat infertility. Apart from patients with endometriosis, of whom 20.6% (n = 7) received ART, patients with other infertility subtypes rarely received ART. For subsequent fertility outcome, 94% of them did not achieve a pregnancy. Conclusion: The prevalence of infertility in China is high, but the uptake of treatment is relatively low.

Original languageEnglish
Pages (from-to)917-925
Number of pages9
JournalReproductive BioMedicine Online
Volume38
Issue number6
DOIs
Publication statusPublished - 1 Jun 2019

Keywords

  • Consultation-seeking behaviour
  • Diagnosis
  • Infertility
  • Treatment

Cite this

Zheng, Danni ; Zhou, Zehong ; Li, Rong ; Wu, Hongping ; Xu, Suxin ; Kang, Yuefan ; Cao, Yunxia ; Chen, Xiujuan ; Zhu, Yimin ; Xu, Shuguang ; Chen, Zi Jiang ; Mol, Ben Willem ; Qiao, Jie. / Consultation and treatment behaviour of infertile couples in China : a population-based study. In: Reproductive BioMedicine Online. 2019 ; Vol. 38, No. 6. pp. 917-925.
@article{bb27b28834a94492a328a0db21610a34,
title = "Consultation and treatment behaviour of infertile couples in China: a population-based study",
abstract = "Research question: The prevalence of infertility in couples actively trying to conceive is 25{\%}. What is the consultation-seeking behaviour, diagnosis and related treatment in infertile couples across China? Design: Large cross-sectional population-based study in 2010–2011, in which 25,270 couples from eight provinces/municipalities in China were approached by a multistage stratified cluster sampling strategy. Results: Among the 2680 couples reporting infertility, 1246 infertile couples consulted a fertility doctor. Age of the couple, man's body mass index and women's educational level were found to be associated with consultation behaviour. After the fertility work-up, diagnoses were tubal infertility (n = 353, 28.3{\%}), unexplained infertility (n = 311, 25.0{\%}), male infertility (n = 234, 18.8{\%}), ovulatory disorder (n = 194, 15.6{\%}) and endometriosis (n = 34, 2.7{\%}), while 8.6{\%} (n = 107) were not classified. Most couples received non-assisted reproductive technology (ART) fertility treatment (n = 906, 89.3{\%}), with a proportion using traditional Chinese medicine (TCM) (n = 298, 29.4{\%}). Intrauterine insemination (n = 62, 6.1{\%}) and IVF/intracytoplasmic sperm injection (n = 57, 5.6{\%}) were less frequent. Medical treatment and outcomes among five subtypes of infertility were also reported: about 30{\%} of couples with unexplained infertility (n = 94, 30.3{\%}) or male infertility (n = 67, 29.0{\%}) used TCM to treat infertility. Apart from patients with endometriosis, of whom 20.6{\%} (n = 7) received ART, patients with other infertility subtypes rarely received ART. For subsequent fertility outcome, 94{\%} of them did not achieve a pregnancy. Conclusion: The prevalence of infertility in China is high, but the uptake of treatment is relatively low.",
keywords = "Consultation-seeking behaviour, Diagnosis, Infertility, Treatment",
author = "Danni Zheng and Zehong Zhou and Rong Li and Hongping Wu and Suxin Xu and Yuefan Kang and Yunxia Cao and Xiujuan Chen and Yimin Zhu and Shuguang Xu and Chen, {Zi Jiang} and Mol, {Ben Willem} and Jie Qiao",
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Zheng, D, Zhou, Z, Li, R, Wu, H, Xu, S, Kang, Y, Cao, Y, Chen, X, Zhu, Y, Xu, S, Chen, ZJ, Mol, BW & Qiao, J 2019, 'Consultation and treatment behaviour of infertile couples in China: a population-based study' Reproductive BioMedicine Online, vol. 38, no. 6, pp. 917-925. https://doi.org/10.1016/j.rbmo.2018.11.034

Consultation and treatment behaviour of infertile couples in China : a population-based study. / Zheng, Danni; Zhou, Zehong; Li, Rong; Wu, Hongping; Xu, Suxin; Kang, Yuefan; Cao, Yunxia; Chen, Xiujuan; Zhu, Yimin; Xu, Shuguang; Chen, Zi Jiang; Mol, Ben Willem; Qiao, Jie.

In: Reproductive BioMedicine Online, Vol. 38, No. 6, 01.06.2019, p. 917-925.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Consultation and treatment behaviour of infertile couples in China

T2 - a population-based study

AU - Zheng, Danni

AU - Zhou, Zehong

AU - Li, Rong

AU - Wu, Hongping

AU - Xu, Suxin

AU - Kang, Yuefan

AU - Cao, Yunxia

AU - Chen, Xiujuan

AU - Zhu, Yimin

AU - Xu, Shuguang

AU - Chen, Zi Jiang

AU - Mol, Ben Willem

AU - Qiao, Jie

PY - 2019/6/1

Y1 - 2019/6/1

N2 - Research question: The prevalence of infertility in couples actively trying to conceive is 25%. What is the consultation-seeking behaviour, diagnosis and related treatment in infertile couples across China? Design: Large cross-sectional population-based study in 2010–2011, in which 25,270 couples from eight provinces/municipalities in China were approached by a multistage stratified cluster sampling strategy. Results: Among the 2680 couples reporting infertility, 1246 infertile couples consulted a fertility doctor. Age of the couple, man's body mass index and women's educational level were found to be associated with consultation behaviour. After the fertility work-up, diagnoses were tubal infertility (n = 353, 28.3%), unexplained infertility (n = 311, 25.0%), male infertility (n = 234, 18.8%), ovulatory disorder (n = 194, 15.6%) and endometriosis (n = 34, 2.7%), while 8.6% (n = 107) were not classified. Most couples received non-assisted reproductive technology (ART) fertility treatment (n = 906, 89.3%), with a proportion using traditional Chinese medicine (TCM) (n = 298, 29.4%). Intrauterine insemination (n = 62, 6.1%) and IVF/intracytoplasmic sperm injection (n = 57, 5.6%) were less frequent. Medical treatment and outcomes among five subtypes of infertility were also reported: about 30% of couples with unexplained infertility (n = 94, 30.3%) or male infertility (n = 67, 29.0%) used TCM to treat infertility. Apart from patients with endometriosis, of whom 20.6% (n = 7) received ART, patients with other infertility subtypes rarely received ART. For subsequent fertility outcome, 94% of them did not achieve a pregnancy. Conclusion: The prevalence of infertility in China is high, but the uptake of treatment is relatively low.

AB - Research question: The prevalence of infertility in couples actively trying to conceive is 25%. What is the consultation-seeking behaviour, diagnosis and related treatment in infertile couples across China? Design: Large cross-sectional population-based study in 2010–2011, in which 25,270 couples from eight provinces/municipalities in China were approached by a multistage stratified cluster sampling strategy. Results: Among the 2680 couples reporting infertility, 1246 infertile couples consulted a fertility doctor. Age of the couple, man's body mass index and women's educational level were found to be associated with consultation behaviour. After the fertility work-up, diagnoses were tubal infertility (n = 353, 28.3%), unexplained infertility (n = 311, 25.0%), male infertility (n = 234, 18.8%), ovulatory disorder (n = 194, 15.6%) and endometriosis (n = 34, 2.7%), while 8.6% (n = 107) were not classified. Most couples received non-assisted reproductive technology (ART) fertility treatment (n = 906, 89.3%), with a proportion using traditional Chinese medicine (TCM) (n = 298, 29.4%). Intrauterine insemination (n = 62, 6.1%) and IVF/intracytoplasmic sperm injection (n = 57, 5.6%) were less frequent. Medical treatment and outcomes among five subtypes of infertility were also reported: about 30% of couples with unexplained infertility (n = 94, 30.3%) or male infertility (n = 67, 29.0%) used TCM to treat infertility. Apart from patients with endometriosis, of whom 20.6% (n = 7) received ART, patients with other infertility subtypes rarely received ART. For subsequent fertility outcome, 94% of them did not achieve a pregnancy. Conclusion: The prevalence of infertility in China is high, but the uptake of treatment is relatively low.

KW - Consultation-seeking behaviour

KW - Diagnosis

KW - Infertility

KW - Treatment

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