Consideration on step duration to assess open-loop static characteristics of the carotid sinus baroreflex in rats

Toru Kawada; Shuji Shimizu; Yusuke Sata; Atsunori Kamiya; Kenji Sunagawa; Masaru Sugimachi

doi:10.1109/IEMBS.2011.6090155

Consideration on step duration to assess open-loop static characteristics of the carotid sinus baroreflex in rats

Toru Kawada
, Shuji Shimizu
, Yusuke Sata
, Atsunori Kamiya
, Kenji Sunagawa
, Masaru Sugimachi

Research output: Chapter in Book/Report/Conference proceeding › Conference Paper › Research › peer-review

3 Citations (Scopus)

Abstract

The carotid sinus baroreflex is one of the most important negative feedback systems to stabilize arterial pressure. Although static characteristics of the carotid sinus baroreflex can be assessed by using a stepwise input protocol under baroreflex open-loop conditions, the step duration has been determined empirically. In the present study, we examined the effects of different time windows (5-10, 15-20, 25-30, 35-40, 45-50, and 55-60 s) on the static characteristics estimated by using a 60-s stepwise input protocol in 10 anesthetized rats. Based on the results, we compared the static characteristics between actual 60-s and 20-s stepwise input protocols. Most of the parameters of the static characteristics did not differ significantly between the 60-s and 20-s stepwise input protocols, suggesting that the open-loop baroreflex static characteristics can be estimated by using a stepwise input with the step duration as short as 20 s in normal rats.

Original language	English
Title of host publication	33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011
Publisher	IEEE, Institute of Electrical and Electronics Engineers
Pages	689-692
Number of pages	4
Volume	2011
ISBN (Print)	9781424441211
DOIs	https://doi.org/10.1109/IEMBS.2011.6090155
Publication status	Published - 2011
Externally published	Yes
Event	International Conference of the IEEE Engineering in Medicine and Biology Society 2011 - Boston, United States of America Duration: 30 Aug 2011 → 3 Sept 2011 Conference number: 33rd https://ieeexplore.ieee.org/xpl/conhome/6067544/proceeding (Proceedings)

Conference

Conference	International Conference of the IEEE Engineering in Medicine and Biology Society 2011
Abbreviated title	EMBC 2011
Country/Territory	United States of America
City	Boston
Period	30/08/11 → 3/09/11
Internet address	https://ieeexplore.ieee.org/xpl/conhome/6067544/proceeding (Proceedings)

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10.1109/IEMBS.2011.6090155

Cite this

Kawada, T., Shimizu, S., Sata, Y., Kamiya, A., Sunagawa, K., & Sugimachi, M. (2011). Consideration on step duration to assess open-loop static characteristics of the carotid sinus baroreflex in rats. In 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011 (Vol. 2011, pp. 689-692). IEEE, Institute of Electrical and Electronics Engineers. https://doi.org/10.1109/IEMBS.2011.6090155

@inproceedings{e690c358bb4c4bd2ad58fc7dd579dae8,

title = "Consideration on step duration to assess open-loop static characteristics of the carotid sinus baroreflex in rats",

abstract = "The carotid sinus baroreflex is one of the most important negative feedback systems to stabilize arterial pressure. Although static characteristics of the carotid sinus baroreflex can be assessed by using a stepwise input protocol under baroreflex open-loop conditions, the step duration has been determined empirically. In the present study, we examined the effects of different time windows (5-10, 15-20, 25-30, 35-40, 45-50, and 55-60 s) on the static characteristics estimated by using a 60-s stepwise input protocol in 10 anesthetized rats. Based on the results, we compared the static characteristics between actual 60-s and 20-s stepwise input protocols. Most of the parameters of the static characteristics did not differ significantly between the 60-s and 20-s stepwise input protocols, suggesting that the open-loop baroreflex static characteristics can be estimated by using a stepwise input with the step duration as short as 20 s in normal rats.",

author = "Toru Kawada and Shuji Shimizu and Yusuke Sata and Atsunori Kamiya and Kenji Sunagawa and Masaru Sugimachi",

year = "2011",

doi = "10.1109/IEMBS.2011.6090155",

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booktitle = "33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011",

publisher = "IEEE, Institute of Electrical and Electronics Engineers",

address = "United States of America",

note = "International Conference of the IEEE Engineering in Medicine and Biology Society 2011, EMBC 2011 ; Conference date: 30-08-2011 Through 03-09-2011",

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Kawada, T, Shimizu, S, Sata, Y, Kamiya, A, Sunagawa, K & Sugimachi, M 2011, Consideration on step duration to assess open-loop static characteristics of the carotid sinus baroreflex in rats. in 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011. vol. 2011, IEEE, Institute of Electrical and Electronics Engineers, pp. 689-692, International Conference of the IEEE Engineering in Medicine and Biology Society 2011, Boston, Massachusetts, United States of America, 30/08/11. https://doi.org/10.1109/IEMBS.2011.6090155

Consideration on step duration to assess open-loop static characteristics of the carotid sinus baroreflex in rats. / Kawada, Toru; Shimizu, Shuji; Sata, Yusuke et al.
33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011. Vol. 2011 IEEE, Institute of Electrical and Electronics Engineers, 2011. p. 689-692.

Research output: Chapter in Book/Report/Conference proceeding › Conference Paper › Research › peer-review

TY - GEN

T1 - Consideration on step duration to assess open-loop static characteristics of the carotid sinus baroreflex in rats

AU - Kawada, Toru

AU - Shimizu, Shuji

AU - Sata, Yusuke

AU - Kamiya, Atsunori

AU - Sunagawa, Kenji

AU - Sugimachi, Masaru

N1 - Conference code: 33rd

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N2 - The carotid sinus baroreflex is one of the most important negative feedback systems to stabilize arterial pressure. Although static characteristics of the carotid sinus baroreflex can be assessed by using a stepwise input protocol under baroreflex open-loop conditions, the step duration has been determined empirically. In the present study, we examined the effects of different time windows (5-10, 15-20, 25-30, 35-40, 45-50, and 55-60 s) on the static characteristics estimated by using a 60-s stepwise input protocol in 10 anesthetized rats. Based on the results, we compared the static characteristics between actual 60-s and 20-s stepwise input protocols. Most of the parameters of the static characteristics did not differ significantly between the 60-s and 20-s stepwise input protocols, suggesting that the open-loop baroreflex static characteristics can be estimated by using a stepwise input with the step duration as short as 20 s in normal rats.

AB - The carotid sinus baroreflex is one of the most important negative feedback systems to stabilize arterial pressure. Although static characteristics of the carotid sinus baroreflex can be assessed by using a stepwise input protocol under baroreflex open-loop conditions, the step duration has been determined empirically. In the present study, we examined the effects of different time windows (5-10, 15-20, 25-30, 35-40, 45-50, and 55-60 s) on the static characteristics estimated by using a 60-s stepwise input protocol in 10 anesthetized rats. Based on the results, we compared the static characteristics between actual 60-s and 20-s stepwise input protocols. Most of the parameters of the static characteristics did not differ significantly between the 60-s and 20-s stepwise input protocols, suggesting that the open-loop baroreflex static characteristics can be estimated by using a stepwise input with the step duration as short as 20 s in normal rats.

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BT - 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011

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T2 - International Conference of the IEEE Engineering in Medicine and Biology Society 2011

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ER -

Kawada T, Shimizu S, Sata Y, Kamiya A, Sunagawa K, Sugimachi M. Consideration on step duration to assess open-loop static characteristics of the carotid sinus baroreflex in rats. In 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011. Vol. 2011. IEEE, Institute of Electrical and Electronics Engineers. 2011. p. 689-692 doi: 10.1109/IEMBS.2011.6090155

Consideration on step duration to assess open-loop static characteristics of the carotid sinus baroreflex in rats

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