Consensus guidelines for the treatment of yeast infections in the haematology, oncology and intensive care setting, 2014

Sharon C A Chen, Tania Christine Sorrell, Christina Catherine Chang, Emma Paige, Penelope A Bryant, Monica Anne Slavin

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44 Citations (Scopus)


Pathogenic yeast forms are commonly associated with invasive fungal disease in the immunocompromised host, including patients with haematological malignancies and patients of haemopoietic stem cell transplants. Yeasts include the Candida spp., Cryptococcus spp., Pneumocystis jirovecii and some lesser-known pathogens. Candida species remain the most common cause of invasive yeast infections (and the most common human pathogenic fungi). These guidelines present evidence-based recommendations for the antifungal management of established, invasive yeast infections in adult and paediatric patients in the haematology/oncology setting. Consideration is also given to the critically ill patient in intensive care units, including the neonatal intensive care unit. Evidence for pre-emptive or diagnostic-driven antifungal therapy is also discussed. For the purposes of this paper, invasive yeast diseases are categorised under the headings of invasive candidiasis, cryptococcosis and uncommon yeast infections. Specific recommendations for the management of Pneumocystis jirovecii are presented in an accompanying article (see consensus guidelines by Cooley etal. appearing elsewhere in this supplement).
Original languageEnglish
Pages (from-to)1315 - 1332
Number of pages18
JournalInternal Medicine Journal
Issue number12
Publication statusPublished - 2014

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