Conformational selection of inhibitors and substrates by proteolytic enzymes: Implications for drug design and polypeptide processing

David P Fairlie; J D Tyndall; R C Reid; A K Wong; Giovanni Abbenante; Martin Scanlon; Darren R March; D A Bergman; C L Chai; B A Burkett

Conformational selection of inhibitors and substrates by proteolytic enzymes: Implications for drug design and polypeptide processing

David P Fairlie, J D Tyndall, R C Reid, A K Wong, Giovanni Abbenante, Martin Scanlon, Darren R March, D A Bergman, C L Chai, B A Burkett

Research output: Contribution to journal › Article › Research › peer-review

152 Citations (Scopus)

Original language	English
Pages (from-to)	1271 - 1281
Number of pages	11
Journal	Journal of Medicinal Chemistry
Volume	43
Publication status	Published - 2000
Externally published	Yes

Cite this

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title = "Conformational selection of inhibitors and substrates by proteolytic enzymes: Implications for drug design and polypeptide processing",

author = "Fairlie, {David P} and Tyndall, {J D} and Reid, {R C} and Wong, {A K} and Giovanni Abbenante and Martin Scanlon and March, {Darren R} and Bergman, {D A} and Chai, {C L} and Burkett, {B A}",

year = "2000",

language = "English",

volume = "43",

pages = "1271 -- 1281",

journal = "Journal of Medicinal Chemistry",

issn = "0022-2623",

publisher = "American Chemical Society",

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T1 - Conformational selection of inhibitors and substrates by proteolytic enzymes: Implications for drug design and polypeptide processing

AU - Fairlie, David P

AU - Tyndall, J D

AU - Reid, R C

AU - Wong, A K

AU - Abbenante, Giovanni

AU - Scanlon, Martin

AU - March, Darren R

AU - Bergman, D A

AU - Chai, C L

AU - Burkett, B A

PY - 2000

Y1 - 2000

UR - http://pubs.acs.org.ezproxy.lib.monash.edu.au/doi/pdf/10.1021/jm990315t

M3 - Article

SN - 0022-2623

VL - 43

SP - 1271

EP - 1281

JO - Journal of Medicinal Chemistry

JF - Journal of Medicinal Chemistry

ER -

Conformational selection of inhibitors and substrates by proteolytic enzymes: Implications for drug design and polypeptide processing

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