Conformational energy calculations and electrostatic potentials of dihydrofolate reductase ligands: relevance to mode of binding and species specificity

Peter R Andrews; Maruse Sadek; M Joy Spark; David Winkler

doi:10.1021/jm00155a020

Conformational energy calculations and electrostatic potentials of dihydrofolate reductase ligands: relevance to mode of binding and species specificity

Peter R Andrews
, Maruse Sadek
, M Joy Spark
, David Winkler

Research output: Contribution to journal › Article › Research › peer-review

Original language	English
Pages (from-to)	698-708
Number of pages	11
Journal	Journal of Medicinal Chemistry
Volume	29
Issue number	5
DOIs	https://doi.org/10.1021/jm00155a020
Publication status	Published - 1986
Externally published	Yes

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10.1021/jm00155a020

Cite this

@article{ab491618ffae4a2cb9aea33c52c9c4f7,

title = "Conformational energy calculations and electrostatic potentials of dihydrofolate reductase ligands: relevance to mode of binding and species specificity",

author = "Andrews, \{Peter R\} and Maruse Sadek and Spark, \{M Joy\} and David Winkler",

year = "1986",

doi = "10.1021/jm00155a020",

language = "English",

volume = "29",

pages = "698--708",

journal = "Journal of Medicinal Chemistry",

issn = "0022-2623",

publisher = "American Chemical Society",

number = "5",

}

TY - JOUR

T1 - Conformational energy calculations and electrostatic potentials of dihydrofolate reductase ligands: relevance to mode of binding and species specificity

AU - Andrews, Peter R

AU - Sadek, Maruse

AU - Spark, M Joy

AU - Winkler, David

PY - 1986

Y1 - 1986

U2 - 10.1021/jm00155a020

DO - 10.1021/jm00155a020

M3 - Article

SN - 0022-2623

VL - 29

SP - 698

EP - 708

JO - Journal of Medicinal Chemistry

JF - Journal of Medicinal Chemistry

IS - 5

ER -