Conformational energy calculations and electrostatic potentials of dihydrofolate reductase ligands: relevance to mode of binding and species specificity

Peter R Andrews, Maruse Sadek, M Joy Spark, David Winkler

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)
Original languageEnglish
Pages (from-to)698-708
Number of pages11
JournalJournal of Medicinal Chemistry
Volume29
Issue number5
DOIs
Publication statusPublished - 1986

Cite this

@article{ab491618ffae4a2cb9aea33c52c9c4f7,
title = "Conformational energy calculations and electrostatic potentials of dihydrofolate reductase ligands: relevance to mode of binding and species specificity",
author = "Andrews, {Peter R} and Maruse Sadek and Spark, {M Joy} and David Winkler",
year = "1986",
doi = "10.1021/jm00155a020",
language = "English",
volume = "29",
pages = "698--708",
journal = "Journal of Medicinal Chemistry",
issn = "0022-2623",
publisher = "AMER CHEMICAL SOC",
number = "5",

}

Conformational energy calculations and electrostatic potentials of dihydrofolate reductase ligands: relevance to mode of binding and species specificity. / Andrews, Peter R; Sadek, Maruse; Spark, M Joy; Winkler, David.

In: Journal of Medicinal Chemistry, Vol. 29, No. 5, 1986, p. 698-708.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Conformational energy calculations and electrostatic potentials of dihydrofolate reductase ligands: relevance to mode of binding and species specificity

AU - Andrews, Peter R

AU - Sadek, Maruse

AU - Spark, M Joy

AU - Winkler, David

PY - 1986

Y1 - 1986

U2 - 10.1021/jm00155a020

DO - 10.1021/jm00155a020

M3 - Article

VL - 29

SP - 698

EP - 708

JO - Journal of Medicinal Chemistry

JF - Journal of Medicinal Chemistry

SN - 0022-2623

IS - 5

ER -