Conflict-induced behavioural adjustment: A clue to the executive functions of the prefrontal cortex

Farshad Alizadeh Mansouri, Keiji Tanaka, Mark J Buckley

Research output: Contribution to journalArticleResearchpeer-review

325 Citations (Scopus)


The behavioural adjustment that follows the experience of conflict has been extensively studied in humans, leading to influential models of executive-control adjustment. Recent studies have revealed striking similarities in conflict-induced behavioural adjustment between humans and monkeys, indicating that monkeys can provide a model to study the underlying neural substrates and mechanisms of such behaviour. These studies have advanced our knowledge about the role of different prefrontal brain regions, including the anterior cingulate cortex (ACC) and the dorsolateral prefrontal cortex (DLPFC), in executive-control adjustment and suggest a pivotal role for the DLPFC in the dynamic tuning of executive control and, consequently, in behavioural adaptation to changing environments.
Original languageEnglish
Pages (from-to)141 - 152
Number of pages12
JournalNature Reviews Neuroscience
Issue number2
Publication statusPublished - 2009
Externally publishedYes

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