Confirmed microsporidial graft infection in a HIV-negative renal transplant recipient

A case report and review of the literature

Research output: Contribution to journalArticleOtherpeer-review

Abstract

Microsporidia are intracellular organisms most commonly known to cause opportunistic infection in patients with human immunodeficiency virus (HIV). There have been several case reports of infection in solid organ and bone marrow transplant recipients. Here, we report a case of a non-HIV–infected renal transplant patient with microsporidiosis of the renal tract associated with acute graft dysfunction. We also review the literature of 12 previously reported cases of microsporidiosis in patients with renal transplants who had described graft involvement. We review the pattern of illness as well as the common renal biopsy features when microsporidial infection is associated with renal graft infection.

Original languageEnglish
Article numbere12888
Number of pages6
JournalTransplant Infectious Disease
Volume20
Issue number3
DOIs
Publication statusPublished - 1 Jun 2018

Keywords

  • graft infection
  • microsporidiosis
  • renal transplant

Cite this

@article{3c88c6d1716a4792b67f72bf83756a1f,
title = "Confirmed microsporidial graft infection in a HIV-negative renal transplant recipient: A case report and review of the literature",
abstract = "Microsporidia are intracellular organisms most commonly known to cause opportunistic infection in patients with human immunodeficiency virus (HIV). There have been several case reports of infection in solid organ and bone marrow transplant recipients. Here, we report a case of a non-HIV–infected renal transplant patient with microsporidiosis of the renal tract associated with acute graft dysfunction. We also review the literature of 12 previously reported cases of microsporidiosis in patients with renal transplants who had described graft involvement. We review the pattern of illness as well as the common renal biopsy features when microsporidial infection is associated with renal graft infection.",
keywords = "graft infection, microsporidiosis, renal transplant",
author = "M. Brown and A. Longano and C. Dendle and Polkinghorne, {K. R.} and J. Kanellis",
year = "2018",
month = "6",
day = "1",
doi = "10.1111/tid.12888",
language = "English",
volume = "20",
journal = "Transplant Infectious Disease",
issn = "1398-2273",
publisher = "Wiley-Blackwell",
number = "3",

}

TY - JOUR

T1 - Confirmed microsporidial graft infection in a HIV-negative renal transplant recipient

T2 - A case report and review of the literature

AU - Brown, M.

AU - Longano, A.

AU - Dendle, C.

AU - Polkinghorne, K. R.

AU - Kanellis, J.

PY - 2018/6/1

Y1 - 2018/6/1

N2 - Microsporidia are intracellular organisms most commonly known to cause opportunistic infection in patients with human immunodeficiency virus (HIV). There have been several case reports of infection in solid organ and bone marrow transplant recipients. Here, we report a case of a non-HIV–infected renal transplant patient with microsporidiosis of the renal tract associated with acute graft dysfunction. We also review the literature of 12 previously reported cases of microsporidiosis in patients with renal transplants who had described graft involvement. We review the pattern of illness as well as the common renal biopsy features when microsporidial infection is associated with renal graft infection.

AB - Microsporidia are intracellular organisms most commonly known to cause opportunistic infection in patients with human immunodeficiency virus (HIV). There have been several case reports of infection in solid organ and bone marrow transplant recipients. Here, we report a case of a non-HIV–infected renal transplant patient with microsporidiosis of the renal tract associated with acute graft dysfunction. We also review the literature of 12 previously reported cases of microsporidiosis in patients with renal transplants who had described graft involvement. We review the pattern of illness as well as the common renal biopsy features when microsporidial infection is associated with renal graft infection.

KW - graft infection

KW - microsporidiosis

KW - renal transplant

UR - http://www.scopus.com/inward/record.url?scp=85044935996&partnerID=8YFLogxK

U2 - 10.1111/tid.12888

DO - 10.1111/tid.12888

M3 - Article

VL - 20

JO - Transplant Infectious Disease

JF - Transplant Infectious Disease

SN - 1398-2273

IS - 3

M1 - e12888

ER -