Conditioned fear to context: Cardiovascular and locomotor correlates in mice

Christopher Choy; Carolina Chavez; Dmitry N Mayorov

doi:10.1016/j.autneu.2009.05.227

Conditioned fear to context: Cardiovascular and locomotor correlates in mice

Christopher Choy, Carolina Chavez, Dmitry N Mayorov

Research output: Contribution to conference › Abstract

Abstract

Conditioned fear to context is the fear response evoked by re-exposure to an environment that was previously paired with an aversive stimulus. Evidence indicates that a long (up to 1 h) conditioned fear response to context is observed in the rat, and that this response is accompanied by strong and persistent increases in mean arterial pressure (MAP) and an immobile behaviour known as freezing [1]. The aim of the present study was to develop a context fear conditioning procedure in mice, and to examine whether this type of conditioning is associated with a sustained cardiovascular activation and behavioural changes in this species.

Original language	English
Pages	118-118
Number of pages	1
DOIs	https://doi.org/10.1016/j.autneu.2009.05.227
Publication status	Published - 2009
Externally published	Yes

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10.1016/j.autneu.2009.05.227

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title = "Conditioned fear to context: Cardiovascular and locomotor correlates in mice",

abstract = "Conditioned fear to context is the fear response evoked by re-exposure to an environment that was previously paired with an aversive stimulus. Evidence indicates that a long (up to 1 h) conditioned fear response to context is observed in the rat, and that this response is accompanied by strong and persistent increases in mean arterial pressure (MAP) and an immobile behaviour known as freezing [1]. The aim of the present study was to develop a context fear conditioning procedure in mice, and to examine whether this type of conditioning is associated with a sustained cardiovascular activation and behavioural changes in this species.",

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doi = "10.1016/j.autneu.2009.05.227",

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N2 - Conditioned fear to context is the fear response evoked by re-exposure to an environment that was previously paired with an aversive stimulus. Evidence indicates that a long (up to 1 h) conditioned fear response to context is observed in the rat, and that this response is accompanied by strong and persistent increases in mean arterial pressure (MAP) and an immobile behaviour known as freezing [1]. The aim of the present study was to develop a context fear conditioning procedure in mice, and to examine whether this type of conditioning is associated with a sustained cardiovascular activation and behavioural changes in this species.

AB - Conditioned fear to context is the fear response evoked by re-exposure to an environment that was previously paired with an aversive stimulus. Evidence indicates that a long (up to 1 h) conditioned fear response to context is observed in the rat, and that this response is accompanied by strong and persistent increases in mean arterial pressure (MAP) and an immobile behaviour known as freezing [1]. The aim of the present study was to develop a context fear conditioning procedure in mice, and to examine whether this type of conditioning is associated with a sustained cardiovascular activation and behavioural changes in this species.

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