Concordance of chlamydia infections of the rectum and urethra in same-sex male partnerships

A cross-sectional analysis

Vincent J. Cornelisse, Christopher J. Sherman, Jane S. Hocking, Henrietta Williams, Lei Zhang, Marcus Y. Chen, Catriona S. Bradshaw, Christopher K. Fairley, Eric P. F. Chow

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Abstract

Background: Our study aimed to describe the concordance of chlamydia infections of the rectum and urethra in men who have sex with men (MSM) and their male partners. Methods: This was a cross-sectional study of chlamydia in MSM and their male sexual partners both attending Melbourne Sexual Health Centre (MSHC), Australia, between February 2011 and March 2015. We excluded partnerships where testing for chlamydia at both the rectum and urethra were not undertaken. Results: Our study included 473 partnerships (946 men). 30 men had urethral chlamydia, of whom 14 (47%, 95% CI 28 to 66) had a partner with rectal chlamydia. 46 men had rectal chlamydia, of whom 14 (30%, 95% CI 18 to 46) had a partner with urethral chlamydia. The proportion of men with rectal chlamydia when their partner had urethral chlamydia was significantly higher than the proportion of men with urethral chlamydia when their partner had rectal chlamydia (McNemar's p = 0.02). Conclusions: This is the first study of chlamydia concordance in male sexual partnerships and suggests that transmission of chlamydia between the urethra and rectum may be less efficient than has been reported for transmission between the urethra and cervix in heterosexual couples. It also suggests that transmission from the urethra to the rectum may be more efficient than in the opposite direction.

Original languageEnglish
Article number22
JournalBMC Infectious Diseases
Volume17
Issue number1
DOIs
Publication statusPublished - 5 Jan 2017

Keywords

  • Chlamydia
  • Chlamydia trachomatis [B03.440.190.190.190.750]
  • Couple
  • Disease Transmission
  • Dyad
  • Homosexuality [F01.145.802.975.500]
  • Infectious [N06.850.310]
  • Men who have sex with men
  • Partnership
  • Sexual Partners [M01.778]
  • Transmission

Cite this

@article{e59107070502499eb300fd6a5803b374,
title = "Concordance of chlamydia infections of the rectum and urethra in same-sex male partnerships: A cross-sectional analysis",
abstract = "Background: Our study aimed to describe the concordance of chlamydia infections of the rectum and urethra in men who have sex with men (MSM) and their male partners. Methods: This was a cross-sectional study of chlamydia in MSM and their male sexual partners both attending Melbourne Sexual Health Centre (MSHC), Australia, between February 2011 and March 2015. We excluded partnerships where testing for chlamydia at both the rectum and urethra were not undertaken. Results: Our study included 473 partnerships (946 men). 30 men had urethral chlamydia, of whom 14 (47{\%}, 95{\%} CI 28 to 66) had a partner with rectal chlamydia. 46 men had rectal chlamydia, of whom 14 (30{\%}, 95{\%} CI 18 to 46) had a partner with urethral chlamydia. The proportion of men with rectal chlamydia when their partner had urethral chlamydia was significantly higher than the proportion of men with urethral chlamydia when their partner had rectal chlamydia (McNemar's p = 0.02). Conclusions: This is the first study of chlamydia concordance in male sexual partnerships and suggests that transmission of chlamydia between the urethra and rectum may be less efficient than has been reported for transmission between the urethra and cervix in heterosexual couples. It also suggests that transmission from the urethra to the rectum may be more efficient than in the opposite direction.",
keywords = "Chlamydia, Chlamydia trachomatis [B03.440.190.190.190.750], Couple, Disease Transmission, Dyad, Homosexuality [F01.145.802.975.500], Infectious [N06.850.310], Men who have sex with men, Partnership, Sexual Partners [M01.778], Transmission",
author = "Cornelisse, {Vincent J.} and Sherman, {Christopher J.} and Hocking, {Jane S.} and Henrietta Williams and Lei Zhang and Chen, {Marcus Y.} and Bradshaw, {Catriona S.} and Fairley, {Christopher K.} and Chow, {Eric P. F.}",
year = "2017",
month = "1",
day = "5",
doi = "10.1186/s12879-016-2141-7",
language = "English",
volume = "17",
journal = "BMC Infectious Diseases",
issn = "1471-2334",
publisher = "Springer-Verlag London Ltd.",
number = "1",

}

Concordance of chlamydia infections of the rectum and urethra in same-sex male partnerships : A cross-sectional analysis. / Cornelisse, Vincent J.; Sherman, Christopher J.; Hocking, Jane S.; Williams, Henrietta; Zhang, Lei; Chen, Marcus Y.; Bradshaw, Catriona S.; Fairley, Christopher K.; Chow, Eric P. F.

In: BMC Infectious Diseases, Vol. 17, No. 1, 22, 05.01.2017.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Concordance of chlamydia infections of the rectum and urethra in same-sex male partnerships

T2 - A cross-sectional analysis

AU - Cornelisse, Vincent J.

AU - Sherman, Christopher J.

AU - Hocking, Jane S.

AU - Williams, Henrietta

AU - Zhang, Lei

AU - Chen, Marcus Y.

AU - Bradshaw, Catriona S.

AU - Fairley, Christopher K.

AU - Chow, Eric P. F.

PY - 2017/1/5

Y1 - 2017/1/5

N2 - Background: Our study aimed to describe the concordance of chlamydia infections of the rectum and urethra in men who have sex with men (MSM) and their male partners. Methods: This was a cross-sectional study of chlamydia in MSM and their male sexual partners both attending Melbourne Sexual Health Centre (MSHC), Australia, between February 2011 and March 2015. We excluded partnerships where testing for chlamydia at both the rectum and urethra were not undertaken. Results: Our study included 473 partnerships (946 men). 30 men had urethral chlamydia, of whom 14 (47%, 95% CI 28 to 66) had a partner with rectal chlamydia. 46 men had rectal chlamydia, of whom 14 (30%, 95% CI 18 to 46) had a partner with urethral chlamydia. The proportion of men with rectal chlamydia when their partner had urethral chlamydia was significantly higher than the proportion of men with urethral chlamydia when their partner had rectal chlamydia (McNemar's p = 0.02). Conclusions: This is the first study of chlamydia concordance in male sexual partnerships and suggests that transmission of chlamydia between the urethra and rectum may be less efficient than has been reported for transmission between the urethra and cervix in heterosexual couples. It also suggests that transmission from the urethra to the rectum may be more efficient than in the opposite direction.

AB - Background: Our study aimed to describe the concordance of chlamydia infections of the rectum and urethra in men who have sex with men (MSM) and their male partners. Methods: This was a cross-sectional study of chlamydia in MSM and their male sexual partners both attending Melbourne Sexual Health Centre (MSHC), Australia, between February 2011 and March 2015. We excluded partnerships where testing for chlamydia at both the rectum and urethra were not undertaken. Results: Our study included 473 partnerships (946 men). 30 men had urethral chlamydia, of whom 14 (47%, 95% CI 28 to 66) had a partner with rectal chlamydia. 46 men had rectal chlamydia, of whom 14 (30%, 95% CI 18 to 46) had a partner with urethral chlamydia. The proportion of men with rectal chlamydia when their partner had urethral chlamydia was significantly higher than the proportion of men with urethral chlamydia when their partner had rectal chlamydia (McNemar's p = 0.02). Conclusions: This is the first study of chlamydia concordance in male sexual partnerships and suggests that transmission of chlamydia between the urethra and rectum may be less efficient than has been reported for transmission between the urethra and cervix in heterosexual couples. It also suggests that transmission from the urethra to the rectum may be more efficient than in the opposite direction.

KW - Chlamydia

KW - Chlamydia trachomatis [B03.440.190.190.190.750]

KW - Couple

KW - Disease Transmission

KW - Dyad

KW - Homosexuality [F01.145.802.975.500]

KW - Infectious [N06.850.310]

KW - Men who have sex with men

KW - Partnership

KW - Sexual Partners [M01.778]

KW - Transmission

UR - http://www.scopus.com/inward/record.url?scp=85008394518&partnerID=8YFLogxK

U2 - 10.1186/s12879-016-2141-7

DO - 10.1186/s12879-016-2141-7

M3 - Article

VL - 17

JO - BMC Infectious Diseases

JF - BMC Infectious Diseases

SN - 1471-2334

IS - 1

M1 - 22

ER -