Abstract
Dendrimers are new hyperbranched globular and three-dimensional nanocarrier. Dendrimer nanocarriers are emergent as most attractive nanocarrier for gene and drug delivery vector. Availability of multiple surface functional groups allow conjugation of targeting moieties which can attract to receptors overexpressed on various cancer cells. It can be concluded that dendrimers show substantial potential as a versatile carrier for bioactives. However, the landing of dendrimer from seat of chemist to formulation desk is still far from complete. Interdisciplinary vision on dendrimer combination with other nanocarriers can be arise as a satisfying strategy. However, the toxicity of the constituents of nanohybrids, vis-a-vis the hybrid itself, will have to be discovered and recognized, if not ruled out.
Original language | English |
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Title of host publication | Dendrimer-Based Nanotherapeutics |
Editors | Prasjant Kesharwani |
Place of Publication | United Kingdom |
Publisher | Elsevier |
Chapter | 25 |
Pages | 449-458 |
Number of pages | 10 |
ISBN (Electronic) | 9780128212509 |
DOIs | |
Publication status | Published - 2021 |
Keywords
- Biocompatibility
- Dendrimer
- Drug delivery
- Gene delivery
- Nanoparticle
- PAMAM
- Surface engineering
- Toxicity