Computed tomography imaging for subclinical leaflet thrombosis following surgical and transcatheter aortic valve replacement

Hashrul N. Rashid; Ronak Rajani; Jonathon Leipsic; Pal Maurovitch-Horvat; Tiffany Patterson; Simon Redwood; Jack Lee; Harriet Hurrell; Stephen J. Nicholls; Arthur Nasis; Sujith Seneviratne; James D. Cameron; Bernard Prendergast; Robert P. Gooley

doi:10.1016/j.jcct.2022.11.001

Computed tomography imaging for subclinical leaflet thrombosis following surgical and transcatheter aortic valve replacement

Hashrul N. Rashid, Ronak Rajani, Jonathon Leipsic, Pal Maurovitch-Horvat, Tiffany Patterson, Simon Redwood, Jack Lee, Harriet Hurrell, Stephen J. Nicholls, Arthur Nasis, Sujith Seneviratne, James D. Cameron, Bernard Prendergast, Robert P. Gooley

Research output: Contribution to journal › Review Article › Research › peer-review

Abstract

Subclinical leaflet thrombosis (LT) may occur following surgical and transcatheter aortic valve replacement. Computed tomography (CT) has become an established imaging modality to diagnose subclinical LT following bioprosthetic aortic valve replacement. Even so, there is a limited (but growing) experience in utilising CT imaging for this indication. This review emphasises a systematic approach to acquiring and analysing CT imaging for subclinical LT, highlighting evidence surrounding clinical sequelae of subclinical LT and anti-thrombotic implications following diagnosis.

Original language	English
Pages (from-to)	2-10
Number of pages	9
Journal	Journal of Cardiovascular Computed Tomography
Volume	17
Issue number	1
DOIs	https://doi.org/10.1016/j.jcct.2022.11.001
Publication status	Published - Jan 2023

Keywords

Aortic stenosis
Aortic valve replacement
Computed tomography
Leaflet thrombosis
TAVR

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10.1016/j.jcct.2022.11.001

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Rashid, H. N., Rajani, R., Leipsic, J., Maurovitch-Horvat, P., Patterson, T., Redwood, S., Lee, J., Hurrell, H., Nicholls, S. J., Nasis, A., Seneviratne, S., Cameron, J. D., Prendergast, B., & Gooley, R. P. (2023). Computed tomography imaging for subclinical leaflet thrombosis following surgical and transcatheter aortic valve replacement. Journal of Cardiovascular Computed Tomography, 17(1), 2-10. https://doi.org/10.1016/j.jcct.2022.11.001

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title = "Computed tomography imaging for subclinical leaflet thrombosis following surgical and transcatheter aortic valve replacement",

abstract = "Subclinical leaflet thrombosis (LT) may occur following surgical and transcatheter aortic valve replacement. Computed tomography (CT) has become an established imaging modality to diagnose subclinical LT following bioprosthetic aortic valve replacement. Even so, there is a limited (but growing) experience in utilising CT imaging for this indication. This review emphasises a systematic approach to acquiring and analysing CT imaging for subclinical LT, highlighting evidence surrounding clinical sequelae of subclinical LT and anti-thrombotic implications following diagnosis.",

keywords = "Aortic stenosis, Aortic valve replacement, Computed tomography, Leaflet thrombosis, TAVR",

author = "Rashid, {Hashrul N.} and Ronak Rajani and Jonathon Leipsic and Pal Maurovitch-Horvat and Tiffany Patterson and Simon Redwood and Jack Lee and Harriet Hurrell and Nicholls, {Stephen J.} and Arthur Nasis and Sujith Seneviratne and Cameron, {James D.} and Bernard Prendergast and Gooley, {Robert P.}",

note = "Funding Information: Dr Hashrul N Rashid is supported by the Postgraduate Scholarship (Reference No. APP 1191131) from the National Health and Medical Research Council ( NHMRC ) (Sydney, NSW, Australia), Health Professional Scholarship (Reference No. 102452), Postdoctoral Fellowship (Reference No. 105817) and Collaboration & Exchange Award (Reference No. 106369) from the National Heart Foundation of Australia (Sydney, NSW, Australia) and the Kincaid-Smith Scholarship from the Royal Australasian College of Physicians ( RACP ) (Sydney, NSW, Australia). Publisher Copyright: {\textcopyright} 2022",

year = "2023",

month = jan,

doi = "10.1016/j.jcct.2022.11.001",

language = "English",

volume = "17",

pages = "2--10",

journal = "Journal of Cardiovascular Computed Tomography",

issn = "1934-5925",

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Rashid, HN, Rajani, R, Leipsic, J, Maurovitch-Horvat, P, Patterson, T, Redwood, S, Lee, J, Hurrell, H, Nicholls, SJ, Nasis, A, Seneviratne, S, Cameron, JD, Prendergast, B & Gooley, RP 2023, 'Computed tomography imaging for subclinical leaflet thrombosis following surgical and transcatheter aortic valve replacement', Journal of Cardiovascular Computed Tomography, vol. 17, no. 1, pp. 2-10. https://doi.org/10.1016/j.jcct.2022.11.001

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AU - Rashid, Hashrul N.

AU - Rajani, Ronak

AU - Leipsic, Jonathon

AU - Maurovitch-Horvat, Pal

AU - Patterson, Tiffany

AU - Redwood, Simon

AU - Lee, Jack

AU - Hurrell, Harriet

AU - Nicholls, Stephen J.

AU - Nasis, Arthur

AU - Seneviratne, Sujith

AU - Cameron, James D.

AU - Prendergast, Bernard

AU - Gooley, Robert P.

N1 - Funding Information: Dr Hashrul N Rashid is supported by the Postgraduate Scholarship (Reference No. APP 1191131) from the National Health and Medical Research Council ( NHMRC ) (Sydney, NSW, Australia), Health Professional Scholarship (Reference No. 102452), Postdoctoral Fellowship (Reference No. 105817) and Collaboration & Exchange Award (Reference No. 106369) from the National Heart Foundation of Australia (Sydney, NSW, Australia) and the Kincaid-Smith Scholarship from the Royal Australasian College of Physicians ( RACP ) (Sydney, NSW, Australia). Publisher Copyright: © 2022

PY - 2023/1

Y1 - 2023/1

N2 - Subclinical leaflet thrombosis (LT) may occur following surgical and transcatheter aortic valve replacement. Computed tomography (CT) has become an established imaging modality to diagnose subclinical LT following bioprosthetic aortic valve replacement. Even so, there is a limited (but growing) experience in utilising CT imaging for this indication. This review emphasises a systematic approach to acquiring and analysing CT imaging for subclinical LT, highlighting evidence surrounding clinical sequelae of subclinical LT and anti-thrombotic implications following diagnosis.

AB - Subclinical leaflet thrombosis (LT) may occur following surgical and transcatheter aortic valve replacement. Computed tomography (CT) has become an established imaging modality to diagnose subclinical LT following bioprosthetic aortic valve replacement. Even so, there is a limited (but growing) experience in utilising CT imaging for this indication. This review emphasises a systematic approach to acquiring and analysing CT imaging for subclinical LT, highlighting evidence surrounding clinical sequelae of subclinical LT and anti-thrombotic implications following diagnosis.

KW - Aortic stenosis

KW - Aortic valve replacement

KW - Computed tomography

KW - Leaflet thrombosis

KW - TAVR

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JO - Journal of Cardiovascular Computed Tomography

JF - Journal of Cardiovascular Computed Tomography

SN - 1934-5925

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ER -

Computed tomography imaging for subclinical leaflet thrombosis following surgical and transcatheter aortic valve replacement

Abstract

Keywords

Access to Document

Other files and links

Hypoattenuated Leaflet Thickening and Leaflet Thrombrosis following Transcatheter Aortic Valve Replacement

Longitudinal impact of CT-defined leaflet thrombosis on valvular haemodynamics and clinical outcomes following transcatheter aortic valve replacement

Advanced Structural Heart Clinical and Research Fellowship at Guy's & St Thomas Hospital

Cite this

Computed tomography imaging for subclinical leaflet thrombosis following surgical and transcatheter aortic valve replacement

Abstract

Keywords

Access to Document

Other files and links

Projects

Hypoattenuated Leaflet Thickening and Leaflet Thrombrosis following Transcatheter Aortic Valve Replacement

Longitudinal impact of CT-defined leaflet thrombosis on valvular haemodynamics and clinical outcomes following transcatheter aortic valve replacement

Advanced Structural Heart Clinical and Research Fellowship at Guy's & St Thomas Hospital

Cite this