Computational prediction of CNS drug exposure based on a novel in vivo dataset

Christel A S Bergstrom; Susan Ann Charman; Joseph Nicolazzo

doi:10.1007/s11095-012-0806-5

Computational prediction of CNS drug exposure based on a novel in vivo dataset

Christel A S Bergstrom, Susan Ann Charman, Joseph Nicolazzo

Research output: Contribution to journal › Article › Research › peer-review

16 Citations (Scopus)

Abstract

A qualitative computational model has been developed which accurately classifies compounds as being high or low CNS exposure drugs based on rapidly calculated molecular descriptors.

Original language	English
Pages (from-to)	3131 - 3142
Number of pages	12
Journal	Pharmaceutical Research
Volume	29
Issue number	11
DOIs	https://doi.org/10.1007/s11095-012-0806-5
Publication status	Published - 2012

Cite this

Bergstrom, C. A. S., Charman, S. A., & Nicolazzo, J. (2012). Computational prediction of CNS drug exposure based on a novel in vivo dataset. Pharmaceutical Research, 29(11), 3131 - 3142. https://doi.org/10.1007/s11095-012-0806-5

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Access to Document

10.1007/s11095-012-0806-5

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