Abstract
Technological advancements in the field of comprehensive two-dimensional (2D) gas chromatography are discussed. Two serially coupled columns with complementary separation mechanisms, ensuring a high degree of orthogonality, were interfaced using a two-stage thermal modulator, which ensured the comprehensive analysis of the entire solute composition. The role of the modulator is critical in that it is responsible for the quantitative transfer and compression of all solutes, or a representative fraction. The performance of modulators should be rigorously tested, although presently there is no specific protocol for this.
| Original language | English |
|---|---|
| Pages (from-to) | 295-297 |
| Number of pages | 3 |
| Journal | Analytical and Bioanalytical Chemistry |
| Volume | 376 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 1 Jun 2003 |
| Externally published | Yes |
Cite this
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Comprehensive two-dimensional gas chromatography. / Ryan, Danielle; Marriott, Philip.
In: Analytical and Bioanalytical Chemistry, Vol. 376, No. 3, 01.06.2003, p. 295-297.Research output: Contribution to journal › Review Article › Research › peer-review
TY - JOUR
T1 - Comprehensive two-dimensional gas chromatography
AU - Ryan, Danielle
AU - Marriott, Philip
PY - 2003/6/1
Y1 - 2003/6/1
N2 - Technological advancements in the field of comprehensive two-dimensional (2D) gas chromatography are discussed. Two serially coupled columns with complementary separation mechanisms, ensuring a high degree of orthogonality, were interfaced using a two-stage thermal modulator, which ensured the comprehensive analysis of the entire solute composition. The role of the modulator is critical in that it is responsible for the quantitative transfer and compression of all solutes, or a representative fraction. The performance of modulators should be rigorously tested, although presently there is no specific protocol for this.
AB - Technological advancements in the field of comprehensive two-dimensional (2D) gas chromatography are discussed. Two serially coupled columns with complementary separation mechanisms, ensuring a high degree of orthogonality, were interfaced using a two-stage thermal modulator, which ensured the comprehensive analysis of the entire solute composition. The role of the modulator is critical in that it is responsible for the quantitative transfer and compression of all solutes, or a representative fraction. The performance of modulators should be rigorously tested, although presently there is no specific protocol for this.
UR - http://www.scopus.com/inward/record.url?scp=21044432316&partnerID=8YFLogxK
U2 - 10.1007/s00216-003-1934-x
DO - 10.1007/s00216-003-1934-x
M3 - Review Article
AN - SCOPUS:21044432316
VL - 376
SP - 295
EP - 297
JO - Analytical and Bioanalytical Chemistry
JF - Analytical and Bioanalytical Chemistry
SN - 1618-2642
IS - 3
ER -