Complex Signaling Networks Control Coxiella burnetii

David R. Thomas; Hayley J. Newton

doi:10.1128/jb.00013-23

Complex Signaling Networks Control Coxiella burnetii

Research output: Contribution to journal › Comment / Debate › Other › peer-review

Abstract

A recent study by S. Wachter, C. L. Larson, K. Virtaneva, K. Kanakabandi, et al. (J Bacteriol 205:e00416-22, 2023, https://doi.org/10.1128/JB.00416-22) utilizes new technologies to examine the role of two-component systems in Coxiella burnetii. This research demonstrates that the zoonotic pathogen C. burnetii mediates complex transcriptional control, throughout different bacterial phases and environmental conditions, with relatively few regulatory elements.

Original language	English
Number of pages	4
Journal	Journal of Bacteriology
Volume	205
Issue number	3
DOIs	https://doi.org/10.1128/jb.00013-23
Publication status	Published - Mar 2023

Keywords

Coxiella burnetii
CRISPRi
environmental response
signalling
two-component system

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10.1128/jb.00013-23

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title = "Complex Signaling Networks Control Coxiella burnetii",

abstract = "A recent study by S. Wachter, C. L. Larson, K. Virtaneva, K. Kanakabandi, et al. (J Bacteriol 205:e00416-22, 2023, https://doi.org/10.1128/JB.00416-22) utilizes new technologies to examine the role of two-component systems in Coxiella burnetii. This research demonstrates that the zoonotic pathogen C. burnetii mediates complex transcriptional control, throughout different bacterial phases and environmental conditions, with relatively few regulatory elements.",

keywords = "Coxiella burnetii, CRISPRi, environmental response, signalling, two-component system",

author = "Thomas, \{David R.\} and Newton, \{Hayley J.\}",

year = "2023",

month = mar,

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language = "English",

volume = "205",

journal = "Journal of Bacteriology",

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publisher = "American Society for Microbiology",

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AU - Thomas, David R.

AU - Newton, Hayley J.

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AB - A recent study by S. Wachter, C. L. Larson, K. Virtaneva, K. Kanakabandi, et al. (J Bacteriol 205:e00416-22, 2023, https://doi.org/10.1128/JB.00416-22) utilizes new technologies to examine the role of two-component systems in Coxiella burnetii. This research demonstrates that the zoonotic pathogen C. burnetii mediates complex transcriptional control, throughout different bacterial phases and environmental conditions, with relatively few regulatory elements.

KW - Coxiella burnetii

KW - CRISPRi

KW - environmental response

KW - signalling

KW - two-component system

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U2 - 10.1128/jb.00013-23

DO - 10.1128/jb.00013-23

M3 - Comment / Debate

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SN - 1098-5530

VL - 205

JO - Journal of Bacteriology

JF - Journal of Bacteriology

IS - 3

ER -

Complex Signaling Networks Control Coxiella burnetii

Abstract

Keywords

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