Complete genome sequences of nitrofurantoinsensitive and -resistant Escherichia coli ST540 and ST2747 strains

Basil Britto Xavier, Jascha Vervoort, Andrew Stewardson, Niels Adriaenssens, Samuel Coenen, Stephan Harbarth, Herman Goossens, Surbhi Malhotra-Kumar

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Abstract

Widespread multidrug resistance in Escherichia coli has necessitated the reintroduction of older antibiotics, such as nitrofurantoin. However, mechanisms by which resistance to nitrofurantoin emerges in E. coli are not well elucidated. Toward this aim, we sequenced two nitrofurantoin-sensitive E. coli sequence types (ST540 and ST2747) and their four nitrofurantoin-resistant derivatives generated in vitro under aerobic and anaerobic growth conditions.

Original languageEnglish
Article numbere00239-14
Number of pages2
JournalGenomic Announcements
Volume2
Issue number2
DOIs
Publication statusPublished - 2014
Externally publishedYes

Cite this

Xavier, B. B., Vervoort, J., Stewardson, A., Adriaenssens, N., Coenen, S., Harbarth, S., Goossens, H., & Malhotra-Kumar, S. (2014). Complete genome sequences of nitrofurantoinsensitive and -resistant Escherichia coli ST540 and ST2747 strains. Genomic Announcements, 2(2), [e00239-14]. https://doi.org/10.1128/genomeA.00239-14