Comparison of two-dimensional speckle and tissue velocity based strain and validation with harmonic phase magnetic resonance imaging

Goo-Yeong Cho, Jonathan Chan, Rodel Leano, Mark W Strudwick, Thomash H Marwick

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Two-dimensional (2-D) strain (epsilon2-D) on the basis of speckle tracking is a new technique for strain measurement. This study sought to validate epsilon2-D and tissue velocity imaging (TVI)-based strain (epsilonTVI) with tagged harmonic-phase (HARP) magnetic resonance imaging (MRI). Thirty patients (mean age 62 +/- 11 years) with known or suspected ischemic heart disease were evaluated. Wall motion (wall motion score index 1.55 +/- 0.46) was assessed by an expert observer. Three apical images were obtained for longitudinal strain (16 segments) and 3 short-axis images for radial and circumferential strain (18 segments). Radial epsilonTVI was obtained in the posterior wall. HARP MRI was used to measure principal strain, expressed as maximal length change in each direction. Values for epsilon2-D, epsilonTVI, and HARP MRI were comparable for all 3 strain directions and were reduced in dysfunctional segments. The mean difference and correlation between longitudinal epsilon2-D and HARP MRI (2.1 +/- 5.5 , r = 0.51, p
Original languageEnglish
Pages (from-to)1661 - 1666
Number of pages6
JournalAmerican Journal of Cardiology
Issue number11
Publication statusPublished - 2006
Externally publishedYes

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