Comparison of propagation-based phase-contrast CT and absorption-based CT for breast imaging using synchrotron radiation

Seyedamir Tavakoli Taba; Sarah Lewis; Patrycja M. Baran; Benedicta D. Arhatari; Yakov I. Nesterets; Sheridan C. Mayo; Darren Thompson; Jane Fox; Beena Kumar; Zdenka Prodanovic; Daniel Hausermann; Anton Maksimenko; Christopher Hall; Matthew Dimmock; Konstantin M. Pavlov; Andrew Peele; Harry M. Quiney; Darren Lockie; Giuliana Tromba; Timur E. Gureyev; Patrick C. Brennan

doi:10.1117/12.2564053

Comparison of propagation-based phase-contrast CT and absorption-based CT for breast imaging using synchrotron radiation

Seyedamir Tavakoli Taba, Sarah Lewis, Patrycja M. Baran, Benedicta D. Arhatari, Yakov I. Nesterets, Sheridan C. Mayo, Darren Thompson, Jane Fox, Beena Kumar, Zdenka Prodanovic, Daniel Hausermann, Anton Maksimenko, Christopher Hall, Matthew Dimmock, Konstantin M. Pavlov, Andrew Peele, Harry M. Quiney, Darren Lockie, Giuliana Tromba, Timur E. GureyevPatrick C. Brennan

Research output: Chapter in Book/Report/Conference proceeding › Conference Paper › Research › peer-review

Abstract

Propagation-based phase-contrast CT (PB-CT) is a novel imaging technique that visualises variations in both X-ray attenuation and refraction. This study aimed to compare the clinical image quality of breast PB-CT using synchrotron radiation with conventional absorption-based CT (AB-CT), at the same radiation dose. Seven breast mastectomy specimens were scanned and evaluated by a group of 14 radiologists and medical imaging experts who assessed the images based on seven radiological image quality criteria. Visual grading characteristics (VGC) were used to analyse the results and the area under the VGC curve was obtained to measure the differences between the two techniques. For six image quality criteria (overall quality, perceptible contrast, lesion sharpness, normal tissue interfaces, calcification visibility and image noise), PB-CT images were superior to AB-CT images of the same dose (AUC_VGC: 0.704 to 0.914, P≤.05). For the seventh criteria (artefacts), PB-CT images were also rated better than AB-CT images (AUC_VGC: 0.647) but the difference was not significant. The results of this study provide a solid basis for future experimental and clinical protocols of breast PB-CT.

Original language	English
Title of host publication	15th International Workshop on Breast Imaging, IWBI 2020
Editors	Hilde Bosmans, Nicholas Marshall, Chantal Van Ongeval
Place of Publication	Bellingham WA USA
Publisher	SPIE
Number of pages	7
Volume	11513
ISBN (Electronic)	9781510638310
DOIs	https://doi.org/10.1117/12.2564053
Publication status	Published - 22 May 2020
Event	International Workshop on Breast Imaging 2020 - Leuven, Belgium Duration: 25 May 2020 → 27 May 2020 Conference number: 15th

Publication series

Name	Proceedings of SPIE - The International Society for Optical Engineering
Volume	11513
ISSN (Print)	0277-786X
ISSN (Electronic)	1996-756X

Conference

Conference	International Workshop on Breast Imaging 2020
Abbreviated title	IWBI2020
Country/Territory	Belgium
City	Leuven
Period	25/05/20 → 27/05/20

Keywords

Absorption-based CT (AB-CT)
Breast CT
Cancer imaging
Propagation-based phase-contrast CT (PB-CT)
Synchrotron radiation
Visual grading characteristics (VGC)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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Taba, S. T., Lewis, S., Baran, P. M., Arhatari, B. D., Nesterets, Y. I., Mayo, S. C., Thompson, D., Fox, J., Kumar, B., Prodanovic, Z., Hausermann, D., Maksimenko, A., Hall, C., Dimmock, M., Pavlov, K. M., Peele, A., Quiney, H. M., Lockie, D., Tromba, G., ... Brennan, P. C. (2020). Comparison of propagation-based phase-contrast CT and absorption-based CT for breast imaging using synchrotron radiation. In H. Bosmans, N. Marshall, & C. Van Ongeval (Eds.), 15th International Workshop on Breast Imaging, IWBI 2020 (Vol. 11513). Article 115130T (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 11513). SPIE. https://doi.org/10.1117/12.2564053

Taba, Seyedamir Tavakoli ; Lewis, Sarah ; Baran, Patrycja M. et al. / Comparison of propagation-based phase-contrast CT and absorption-based CT for breast imaging using synchrotron radiation. 15th International Workshop on Breast Imaging, IWBI 2020. editor / Hilde Bosmans ; Nicholas Marshall ; Chantal Van Ongeval. Vol. 11513 Bellingham WA USA : SPIE, 2020. (Proceedings of SPIE - The International Society for Optical Engineering).

@inproceedings{3be2985b051d45eda9a73b902679e9cc,

title = "Comparison of propagation-based phase-contrast CT and absorption-based CT for breast imaging using synchrotron radiation",

abstract = "Propagation-based phase-contrast CT (PB-CT) is a novel imaging technique that visualises variations in both X-ray attenuation and refraction. This study aimed to compare the clinical image quality of breast PB-CT using synchrotron radiation with conventional absorption-based CT (AB-CT), at the same radiation dose. Seven breast mastectomy specimens were scanned and evaluated by a group of 14 radiologists and medical imaging experts who assessed the images based on seven radiological image quality criteria. Visual grading characteristics (VGC) were used to analyse the results and the area under the VGC curve was obtained to measure the differences between the two techniques. For six image quality criteria (overall quality, perceptible contrast, lesion sharpness, normal tissue interfaces, calcification visibility and image noise), PB-CT images were superior to AB-CT images of the same dose (AUCVGC: 0.704 to 0.914, P≤.05). For the seventh criteria (artefacts), PB-CT images were also rated better than AB-CT images (AUCVGC: 0.647) but the difference was not significant. The results of this study provide a solid basis for future experimental and clinical protocols of breast PB-CT.",

keywords = "Absorption-based CT (AB-CT), Breast CT, Cancer imaging, Propagation-based phase-contrast CT (PB-CT), Synchrotron radiation, Visual grading characteristics (VGC)",

author = "Taba, {Seyedamir Tavakoli} and Sarah Lewis and Baran, {Patrycja M.} and Arhatari, {Benedicta D.} and Nesterets, {Yakov I.} and Mayo, {Sheridan C.} and Darren Thompson and Jane Fox and Beena Kumar and Zdenka Prodanovic and Daniel Hausermann and Anton Maksimenko and Christopher Hall and Matthew Dimmock and Pavlov, {Konstantin M.} and Andrew Peele and Quiney, {Harry M.} and Darren Lockie and Giuliana Tromba and Gureyev, {Timur E.} and Brennan, {Patrick C.}",

year = "2020",

month = may,

day = "22",

doi = "10.1117/12.2564053",

language = "English",

volume = "11513",

series = "Proceedings of SPIE - The International Society for Optical Engineering",

publisher = "SPIE",

editor = "Hilde Bosmans and Nicholas Marshall and {Van Ongeval}, Chantal",

booktitle = "15th International Workshop on Breast Imaging, IWBI 2020",

address = "United States of America",

note = "International Workshop on Breast Imaging 2020, IWBI2020 ; Conference date: 25-05-2020 Through 27-05-2020",

}

Taba, ST, Lewis, S, Baran, PM, Arhatari, BD, Nesterets, YI, Mayo, SC, Thompson, D, Fox, J, Kumar, B, Prodanovic, Z, Hausermann, D, Maksimenko, A, Hall, C, Dimmock, M, Pavlov, KM, Peele, A, Quiney, HM, Lockie, D, Tromba, G, Gureyev, TE & Brennan, PC 2020, Comparison of propagation-based phase-contrast CT and absorption-based CT for breast imaging using synchrotron radiation. in H Bosmans, N Marshall & C Van Ongeval (eds), 15th International Workshop on Breast Imaging, IWBI 2020. vol. 11513, 115130T, Proceedings of SPIE - The International Society for Optical Engineering, vol. 11513, SPIE, Bellingham WA USA, International Workshop on Breast Imaging 2020, Leuven, Belgium, 25/05/20. https://doi.org/10.1117/12.2564053

Comparison of propagation-based phase-contrast CT and absorption-based CT for breast imaging using synchrotron radiation. / Taba, Seyedamir Tavakoli; Lewis, Sarah; Baran, Patrycja M. et al.
15th International Workshop on Breast Imaging, IWBI 2020. ed. / Hilde Bosmans; Nicholas Marshall; Chantal Van Ongeval. Vol. 11513 Bellingham WA USA: SPIE, 2020. 115130T (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 11513).

Research output: Chapter in Book/Report/Conference proceeding › Conference Paper › Research › peer-review

TY - GEN

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AU - Taba, Seyedamir Tavakoli

AU - Lewis, Sarah

AU - Baran, Patrycja M.

AU - Arhatari, Benedicta D.

AU - Nesterets, Yakov I.

AU - Mayo, Sheridan C.

AU - Thompson, Darren

AU - Fox, Jane

AU - Kumar, Beena

AU - Prodanovic, Zdenka

AU - Hausermann, Daniel

AU - Maksimenko, Anton

AU - Hall, Christopher

AU - Dimmock, Matthew

AU - Pavlov, Konstantin M.

AU - Peele, Andrew

AU - Quiney, Harry M.

AU - Lockie, Darren

AU - Tromba, Giuliana

AU - Gureyev, Timur E.

AU - Brennan, Patrick C.

N1 - Conference code: 15th

PY - 2020/5/22

Y1 - 2020/5/22

N2 - Propagation-based phase-contrast CT (PB-CT) is a novel imaging technique that visualises variations in both X-ray attenuation and refraction. This study aimed to compare the clinical image quality of breast PB-CT using synchrotron radiation with conventional absorption-based CT (AB-CT), at the same radiation dose. Seven breast mastectomy specimens were scanned and evaluated by a group of 14 radiologists and medical imaging experts who assessed the images based on seven radiological image quality criteria. Visual grading characteristics (VGC) were used to analyse the results and the area under the VGC curve was obtained to measure the differences between the two techniques. For six image quality criteria (overall quality, perceptible contrast, lesion sharpness, normal tissue interfaces, calcification visibility and image noise), PB-CT images were superior to AB-CT images of the same dose (AUCVGC: 0.704 to 0.914, P≤.05). For the seventh criteria (artefacts), PB-CT images were also rated better than AB-CT images (AUCVGC: 0.647) but the difference was not significant. The results of this study provide a solid basis for future experimental and clinical protocols of breast PB-CT.

AB - Propagation-based phase-contrast CT (PB-CT) is a novel imaging technique that visualises variations in both X-ray attenuation and refraction. This study aimed to compare the clinical image quality of breast PB-CT using synchrotron radiation with conventional absorption-based CT (AB-CT), at the same radiation dose. Seven breast mastectomy specimens were scanned and evaluated by a group of 14 radiologists and medical imaging experts who assessed the images based on seven radiological image quality criteria. Visual grading characteristics (VGC) were used to analyse the results and the area under the VGC curve was obtained to measure the differences between the two techniques. For six image quality criteria (overall quality, perceptible contrast, lesion sharpness, normal tissue interfaces, calcification visibility and image noise), PB-CT images were superior to AB-CT images of the same dose (AUCVGC: 0.704 to 0.914, P≤.05). For the seventh criteria (artefacts), PB-CT images were also rated better than AB-CT images (AUCVGC: 0.647) but the difference was not significant. The results of this study provide a solid basis for future experimental and clinical protocols of breast PB-CT.

KW - Absorption-based CT (AB-CT)

KW - Breast CT

KW - Cancer imaging

KW - Propagation-based phase-contrast CT (PB-CT)

KW - Synchrotron radiation

KW - Visual grading characteristics (VGC)

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DO - 10.1117/12.2564053

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T3 - Proceedings of SPIE - The International Society for Optical Engineering

BT - 15th International Workshop on Breast Imaging, IWBI 2020

A2 - Bosmans, Hilde

A2 - Marshall, Nicholas

A2 - Van Ongeval, Chantal

PB - SPIE

CY - Bellingham WA USA

T2 - International Workshop on Breast Imaging 2020

Y2 - 25 May 2020 through 27 May 2020

ER -

Taba ST, Lewis S, Baran PM, Arhatari BD, Nesterets YI, Mayo SC et al. Comparison of propagation-based phase-contrast CT and absorption-based CT for breast imaging using synchrotron radiation. In Bosmans H, Marshall N, Van Ongeval C, editors, 15th International Workshop on Breast Imaging, IWBI 2020. Vol. 11513. Bellingham WA USA: SPIE. 2020. 115130T. (Proceedings of SPIE - The International Society for Optical Engineering). doi: 10.1117/12.2564053

Comparison of propagation-based phase-contrast CT and absorption-based CT for breast imaging using synchrotron radiation

Abstract

Publication series

Conference

Keywords

UN SDGs

Access to Document

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