Comparison of preterm and term equivalent age MRI for the evaluation of preterm brain injury

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Objective:To compare information obtained from preterm magnetic resonance imaging (MRI; 31–34 weeks) brain scan to that done at term equivalent age.Study design:Prospective observational study of premature infants with evidence or suspicion of parenchymal brain injury on cranial ultrasound. Brain injury on two scans scored using a scoring system and analyzed.Results:Fourteen infants with a median (range) gestation at birth of 28 (25–29) weeks and birth weight of 1254 (680–1557) grams were studied. There was a strong correlation between the brain injury scores for the two scans (Spearman ρ=0.87, P=0.001) with excellent agreement between two radiologists (interclass correlation coefficient 0.9–0.94). There was also a high level of agreement between the preterm and term MRI two scores (Intraclass correlation coefficient, 0.79 (0.53–0.94)).Conclusions:Preterm MRI is a feasible option for the assessment of preterm brain injury and analysis of data obtained from scan at preterm age is comparable to that obtained at term equivalent age.Journal of Perinatology advance online publication, 6 April 2017; doi:10.1038/jp.2017.39.

Original languageEnglish
Pages (from-to)864-868
Number of pages5
JournalJournal of Perinatology
Volume37
DOIs
Publication statusPublished - 6 Apr 2017

Cite this

@article{6f92799dea1249e6b78034f49d176b29,
title = "Comparison of preterm and term equivalent age MRI for the evaluation of preterm brain injury",
abstract = "Objective:To compare information obtained from preterm magnetic resonance imaging (MRI; 31–34 weeks) brain scan to that done at term equivalent age.Study design:Prospective observational study of premature infants with evidence or suspicion of parenchymal brain injury on cranial ultrasound. Brain injury on two scans scored using a scoring system and analyzed.Results:Fourteen infants with a median (range) gestation at birth of 28 (25–29) weeks and birth weight of 1254 (680–1557) grams were studied. There was a strong correlation between the brain injury scores for the two scans (Spearman ρ=0.87, P=0.001) with excellent agreement between two radiologists (interclass correlation coefficient 0.9–0.94). There was also a high level of agreement between the preterm and term MRI two scores (Intraclass correlation coefficient, 0.79 (0.53–0.94)).Conclusions:Preterm MRI is a feasible option for the assessment of preterm brain injury and analysis of data obtained from scan at preterm age is comparable to that obtained at term equivalent age.Journal of Perinatology advance online publication, 6 April 2017; doi:10.1038/jp.2017.39.",
author = "A. Malhotra and Fahey, {M. C.} and Miranda Davies-Tuck and F. Wong and Elizabeth Carse and G Whiteley and M. Ditchfield",
year = "2017",
month = "4",
day = "6",
doi = "10.1038/jp.2017.39",
language = "English",
volume = "37",
pages = "864--868",
journal = "Journal of Perinatology",
issn = "0743-8346",
publisher = "Nature Publishing Group",

}

Comparison of preterm and term equivalent age MRI for the evaluation of preterm brain injury. / Malhotra, A.; Fahey, M. C.; Davies-Tuck, Miranda; Wong, F.; Carse, Elizabeth; Whiteley, G; Ditchfield, M.

In: Journal of Perinatology, Vol. 37, 06.04.2017, p. 864-868.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Comparison of preterm and term equivalent age MRI for the evaluation of preterm brain injury

AU - Malhotra, A.

AU - Fahey, M. C.

AU - Davies-Tuck, Miranda

AU - Wong, F.

AU - Carse, Elizabeth

AU - Whiteley, G

AU - Ditchfield, M.

PY - 2017/4/6

Y1 - 2017/4/6

N2 - Objective:To compare information obtained from preterm magnetic resonance imaging (MRI; 31–34 weeks) brain scan to that done at term equivalent age.Study design:Prospective observational study of premature infants with evidence or suspicion of parenchymal brain injury on cranial ultrasound. Brain injury on two scans scored using a scoring system and analyzed.Results:Fourteen infants with a median (range) gestation at birth of 28 (25–29) weeks and birth weight of 1254 (680–1557) grams were studied. There was a strong correlation between the brain injury scores for the two scans (Spearman ρ=0.87, P=0.001) with excellent agreement between two radiologists (interclass correlation coefficient 0.9–0.94). There was also a high level of agreement between the preterm and term MRI two scores (Intraclass correlation coefficient, 0.79 (0.53–0.94)).Conclusions:Preterm MRI is a feasible option for the assessment of preterm brain injury and analysis of data obtained from scan at preterm age is comparable to that obtained at term equivalent age.Journal of Perinatology advance online publication, 6 April 2017; doi:10.1038/jp.2017.39.

AB - Objective:To compare information obtained from preterm magnetic resonance imaging (MRI; 31–34 weeks) brain scan to that done at term equivalent age.Study design:Prospective observational study of premature infants with evidence or suspicion of parenchymal brain injury on cranial ultrasound. Brain injury on two scans scored using a scoring system and analyzed.Results:Fourteen infants with a median (range) gestation at birth of 28 (25–29) weeks and birth weight of 1254 (680–1557) grams were studied. There was a strong correlation between the brain injury scores for the two scans (Spearman ρ=0.87, P=0.001) with excellent agreement between two radiologists (interclass correlation coefficient 0.9–0.94). There was also a high level of agreement between the preterm and term MRI two scores (Intraclass correlation coefficient, 0.79 (0.53–0.94)).Conclusions:Preterm MRI is a feasible option for the assessment of preterm brain injury and analysis of data obtained from scan at preterm age is comparable to that obtained at term equivalent age.Journal of Perinatology advance online publication, 6 April 2017; doi:10.1038/jp.2017.39.

UR - http://www.scopus.com/inward/record.url?scp=85017148619&partnerID=8YFLogxK

U2 - 10.1038/jp.2017.39

DO - 10.1038/jp.2017.39

M3 - Article

VL - 37

SP - 864

EP - 868

JO - Journal of Perinatology

JF - Journal of Perinatology

SN - 0743-8346

ER -