Comparative genotypic and phenotypic analysis of surrogate monocytic-like cell lines and human peripheral blood monocytes

Darren Riddy; Emily Goy; Roger Summers; Arthur Christopoulos; Patrick Michael Sexton; Christopher Langmead

Comparative genotypic and phenotypic analysis of surrogate monocytic-like cell lines and human peripheral blood monocytes

Drug Discovery Biology

Research output: Contribution to conference › Poster › peer-review

Abstract

Monocytic-like cell lines (MCLCs), including THP-1 and U-937 cells, are used routinely as surrogates for isolated human peripheral blood monocytes (PBMCs). In recent years these cell lines have been characterised based on mRNA expression levels of ion channels, G protein-coupled receptors and inflammatory mediators.

Original language	English
Number of pages	1
Publication status	Published - 2016
Event	ASCEPT-MPGPCR Joint Scientific Meeting 2016: Therapeutic targeting: right place, right time, right effect - Melbourne Convention & Exhibition Centre, Melbourne, Australia Duration: 27 Nov 2016 → 30 Nov 2016 https://www.asceptasm.com/2016-annual-scientific-meeting/program-workshops/

Conference

Conference	ASCEPT-MPGPCR Joint Scientific Meeting 2016
Abbreviated title	ASCEPT/MPGPCR 2016
Country/Territory	Australia
City	Melbourne
Period	27/11/16 → 30/11/16
Internet address	https://www.asceptasm.com/2016-annual-scientific-meeting/program-workshops/

Cite this

@conference{b485847e1f9f46ec86382cd746926d70,

title = "Comparative genotypic and phenotypic analysis of surrogate monocytic-like cell lines and human peripheral blood monocytes",

abstract = "Monocytic-like cell lines (MCLCs), including THP-1 and U-937 cells, are used routinely as surrogates for isolated human peripheral blood monocytes (PBMCs). In recent years these cell lines have been characterised based on mRNA expression levels of ion channels, G protein-coupled receptors and inflammatory mediators.",

author = "Darren Riddy and Emily Goy and Roger Summers and Arthur Christopoulos and Sexton, \{Patrick Michael\} and Christopher Langmead",

year = "2016",

language = "English",

note = "ASCEPT-MPGPCR Joint Scientific Meeting 2016 : Therapeutic targeting: right place, right time, right effect, ASCEPT/MPGPCR 2016 ; Conference date: 27-11-2016 Through 30-11-2016",

url = "https://www.asceptasm.com/2016-annual-scientific-meeting/program-workshops/",

}

TY - CONF

T1 - Comparative genotypic and phenotypic analysis of surrogate monocytic-like cell lines and human peripheral blood monocytes

AU - Riddy, Darren

AU - Goy, Emily

AU - Summers, Roger

AU - Christopoulos, Arthur

AU - Sexton, Patrick Michael

AU - Langmead, Christopher

PY - 2016

Y1 - 2016

N2 - Monocytic-like cell lines (MCLCs), including THP-1 and U-937 cells, are used routinely as surrogates for isolated human peripheral blood monocytes (PBMCs). In recent years these cell lines have been characterised based on mRNA expression levels of ion channels, G protein-coupled receptors and inflammatory mediators.

AB - Monocytic-like cell lines (MCLCs), including THP-1 and U-937 cells, are used routinely as surrogates for isolated human peripheral blood monocytes (PBMCs). In recent years these cell lines have been characterised based on mRNA expression levels of ion channels, G protein-coupled receptors and inflammatory mediators.

M3 - Poster

T2 - ASCEPT-MPGPCR Joint Scientific Meeting 2016

Y2 - 27 November 2016 through 30 November 2016

ER -