Monocytic-like cell lines (MCLCs), including THP-1 and U-937 cells, are used routinely as surrogates for isolated human peripheral blood monocytes (PBMCs). In recent years these cell lines have been characterised based on mRNA expression levels of ion channels, G protein-coupled receptors and inflammatory mediators.
|Number of pages||1|
|Publication status||Published - 2016|
|Event||ASCEPT-MPGPCR Joint Scientific Meeting 2016: Therapeutic targeting: right place, right time, right effect - Melbourne Convention & Exhibition Centre, Melbourne, Australia|
Duration: 27 Nov 2016 → 30 Nov 2016
|Conference||ASCEPT-MPGPCR Joint Scientific Meeting 2016|
|Abbreviated title||ASCEPT/MPGPCR 2016|
|Period||27/11/16 → 30/11/16|
Riddy, D., Goy, E., Summers, R., Christopoulos, A., Sexton, P. M., & Langmead, C. (2016). Comparative genotypic and phenotypic analysis of surrogate monocytic-like cell lines and human peripheral blood monocytes. Poster session presented at ASCEPT-MPGPCR Joint Scientific Meeting 2016, Melbourne, Australia.