Objective: To assess community pharmacists knowledge, behaviors and experiences relating to Adverse Drug Reaction (ADR) reporting in Saudi Arabia. Methods: A cross-sectional study was conducted using a validated self-administered questionnaire. A convenience sample of 147 community pharmacists working in community pharmacies in Riyadh, Saudi Arabia. Results: The questionnaire was distributed to 147 pharmacists, of whom 104 responded to the survey, a 70.7 response rate. The mean age of participants was 29. years. The majority (n= 101, 98.1 ) had graduated with a bachelorette degree and worked in chain pharmacies (n= 68, 66.7 ). Only 23 (22.1 ) said they were familiar with the ADR reporting process, and only 21 (20.2 ) knew that pharmacists can submit ADR reports online. The majority of the participants (n= 90, 86.5 ) had never reported ADRs. Reasons for not reporting ADRs most importantly included lack of awareness about the method of reporting (n= 22, 45.9 ), misconception that reporting ADRs is the duty of physician and hospital pharmacist (n= 8, 16.6 ) and ADRs in community pharmacies are simple and should not be reported (n= 8, 16.6 ). The most common approach perceived by community pharmacists for managing patients suffering from ADRs was to refer him/her to a physician (n= 80, 76.9 ). Conclusion: The majority of community pharmacists in Riyadh have poor knowledge of the ADR reporting process. Pharmacovigilance authorities should take necessary steps to urgently design interventional programs in order to increase the knowledge and awareness of pharmacists regarding the ADR reporting process.