Combining hiPSCs and Human Genetics: Major Applications in Drug Development

Jin Zhang; Hu Li; Alan Trounson; Joseph C. Wu; Paul Nioi

doi:10.1016/j.stem.2017.07.012

Combining hiPSCs and Human Genetics: Major Applications in Drug Development

Jin Zhang, Hu Li, Alan Trounson, Joseph C. Wu, Paul Nioi

Hudson Institute - Department of Molecular and Translational Science

Research output: Contribution to journal › Comment / Debate › Other › peer-review

10 Citations (Scopus)

Abstract

Merging iPSC models and human genetic research has opened up new avenues in understanding disease mechanisms and target biology, which facilitate exciting translation of this research to many areas of drug development. We highlight recent applications of these combined disciplines and discuss remaining challenges and potential solutions.

Original language	English
Pages (from-to)	161-165
Number of pages	5
Journal	Cell Stem Cell
Volume	21
Issue number	2
DOIs	https://doi.org/10.1016/j.stem.2017.07.012
Publication status	Published - 3 Aug 2017

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10.1016/j.stem.2017.07.012

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title = "Combining hiPSCs and Human Genetics: Major Applications in Drug Development",

abstract = "Merging iPSC models and human genetic research has opened up new avenues in understanding disease mechanisms and target biology, which facilitate exciting translation of this research to many areas of drug development. We highlight recent applications of these combined disciplines and discuss remaining challenges and potential solutions.",

author = "Jin Zhang and Hu Li and Alan Trounson and Wu, {Joseph C.} and Paul Nioi",

year = "2017",

month = aug,

day = "3",

doi = "10.1016/j.stem.2017.07.012",

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journal = "Cell Stem Cell",

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TY - JOUR

T1 - Combining hiPSCs and Human Genetics

T2 - Major Applications in Drug Development

AU - Zhang, Jin

AU - Li, Hu

AU - Trounson, Alan

AU - Wu, Joseph C.

AU - Nioi, Paul

PY - 2017/8/3

Y1 - 2017/8/3

N2 - Merging iPSC models and human genetic research has opened up new avenues in understanding disease mechanisms and target biology, which facilitate exciting translation of this research to many areas of drug development. We highlight recent applications of these combined disciplines and discuss remaining challenges and potential solutions.

AB - Merging iPSC models and human genetic research has opened up new avenues in understanding disease mechanisms and target biology, which facilitate exciting translation of this research to many areas of drug development. We highlight recent applications of these combined disciplines and discuss remaining challenges and potential solutions.

UR - http://www.scopus.com/inward/record.url?scp=85027436641&partnerID=8YFLogxK

U2 - 10.1016/j.stem.2017.07.012

DO - 10.1016/j.stem.2017.07.012

M3 - Comment / Debate

AN - SCOPUS:85027436641

SN - 1934-5909

VL - 21

SP - 161

EP - 165

JO - Cell Stem Cell

JF - Cell Stem Cell

IS - 2

ER -

Combining hiPSCs and Human Genetics: Major Applications in Drug Development

Abstract

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