Abstract
The aim was to analyse data from two randomized controlled trials (RCTs) to determine if an adherence intervention programme for antiretroviral therapy (ART) resulted in a reduction in viral load. A cohort analysis of pre- and post-intervention viral loads and CD4 counts using paired analysis was undertaken on participants who received the intervention programme. Analysis was also undertaken on a control group. The intervention participants had an increase in mean CD4 count (450-478, P = 0.26), and a decline in log viral load (2.48-2.36, P = 0.056). The control group had a decline in mean CD4 counts (596-570, P = 0.53), and an increase in log viral load (2.09-2.11, P = 0.78). The use of an adherence intervention programme is associated with a decrease in mean viral load, which is in contrast to the control group that demonstrated an increase in viral load over time.
Original language | English |
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Pages (from-to) | 257-259 |
Number of pages | 3 |
Journal | International Journal of STD and AIDS |
Volume | 17 |
Issue number | 4 |
DOIs | |
Publication status | Published - 1 Apr 2006 |
Keywords
- Adherence
- Antiretroviral
- HIV
- Intervention