Abstract
The aim was to analyse data from two randomized controlled trials (RCTs) to determine if an adherence intervention programme for antiretroviral therapy (ART) resulted in a reduction in viral load. A cohort analysis of pre- and post-intervention viral loads and CD4 counts using paired analysis was undertaken on participants who received the intervention programme. Analysis was also undertaken on a control group. The intervention participants had an increase in mean CD4 count (450-478, P = 0.26), and a decline in log viral load (2.48-2.36, P = 0.056). The control group had a decline in mean CD4 counts (596-570, P = 0.53), and an increase in log viral load (2.09-2.11, P = 0.78). The use of an adherence intervention programme is associated with a decrease in mean viral load, which is in contrast to the control group that demonstrated an increase in viral load over time.
| Original language | English |
|---|---|
| Pages (from-to) | 257-259 |
| Number of pages | 3 |
| Journal | International Journal of STD and AIDS |
| Volume | 17 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 1 Apr 2006 |
Keywords
- Adherence
- Antiretroviral
- HIV
- Intervention
Cite this
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Cohort analysis of two multidisciplined adherence intervention programmes for patients on antiretroviral therapy. / Doxanakis, A.; Read, T.; Levy, R.; Mijch, A.; Fairley, C. K.
In: International Journal of STD and AIDS, Vol. 17, No. 4, 01.04.2006, p. 257-259.Research output: Contribution to journal › Article › Research › peer-review
TY - JOUR
T1 - Cohort analysis of two multidisciplined adherence intervention programmes for patients on antiretroviral therapy
AU - Doxanakis, A.
AU - Read, T.
AU - Levy, R.
AU - Mijch, A.
AU - Fairley, C. K.
PY - 2006/4/1
Y1 - 2006/4/1
N2 - The aim was to analyse data from two randomized controlled trials (RCTs) to determine if an adherence intervention programme for antiretroviral therapy (ART) resulted in a reduction in viral load. A cohort analysis of pre- and post-intervention viral loads and CD4 counts using paired analysis was undertaken on participants who received the intervention programme. Analysis was also undertaken on a control group. The intervention participants had an increase in mean CD4 count (450-478, P = 0.26), and a decline in log viral load (2.48-2.36, P = 0.056). The control group had a decline in mean CD4 counts (596-570, P = 0.53), and an increase in log viral load (2.09-2.11, P = 0.78). The use of an adherence intervention programme is associated with a decrease in mean viral load, which is in contrast to the control group that demonstrated an increase in viral load over time.
AB - The aim was to analyse data from two randomized controlled trials (RCTs) to determine if an adherence intervention programme for antiretroviral therapy (ART) resulted in a reduction in viral load. A cohort analysis of pre- and post-intervention viral loads and CD4 counts using paired analysis was undertaken on participants who received the intervention programme. Analysis was also undertaken on a control group. The intervention participants had an increase in mean CD4 count (450-478, P = 0.26), and a decline in log viral load (2.48-2.36, P = 0.056). The control group had a decline in mean CD4 counts (596-570, P = 0.53), and an increase in log viral load (2.09-2.11, P = 0.78). The use of an adherence intervention programme is associated with a decrease in mean viral load, which is in contrast to the control group that demonstrated an increase in viral load over time.
KW - Adherence
KW - Antiretroviral
KW - HIV
KW - Intervention
UR - http://www.scopus.com/inward/record.url?scp=33645542033&partnerID=8YFLogxK
U2 - 10.1258/095646206776253499
DO - 10.1258/095646206776253499
M3 - Article
C2 - 16595049
AN - SCOPUS:33645542033
VL - 17
SP - 257
EP - 259
JO - International Journal of STD and AIDS
JF - International Journal of STD and AIDS
SN - 0956-4624
IS - 4
ER -