TY - JOUR
T1 - Cognitive recovery and development after traumatic brain injury in childhood
T2 - A person-oriented, longitudinal study
AU - Jonsson, Catherine Aaro
AU - Catroppa, Cathy
AU - Godfrey, Celia
AU - Smedler, Ann Charlotte
AU - Anderson, Vicki
PY - 2013/1/15
Y1 - 2013/1/15
N2 - Influence of childhood traumatic brain injury (TBI) on cognitive recovery and subsequent development is poorly understood. In this longitudinal study we used cluster analysis to explore acute stage individual profiles of injury age and cognition in 118 children with traumatic brain injury. Repeated measures of cognitive function were conducted at 30 months, indicating recovery, and 10 years post-injury, indicating development. Nine clusters were identified. Recovery was evident in three clusters, two of them with low functioning profiles. Developmental gains occurred for three clusters and an acute profile of higher freedom from distractibility (FFD) and lower processing speed (PS) was related to positive differences. One cluster, average low functioning and especially low verbal comprehension, demonstrated a slower development than peers. This suggests that developmental change after TBI in childhood takes place on a continuum, with both chance of long-term catching up, and risk of poor development. An acute profile of higher FFD and lower PS seemed to reflect injury consequences and were followed by developmental gains. These results challenge previous findings, and warrant further investigation.
AB - Influence of childhood traumatic brain injury (TBI) on cognitive recovery and subsequent development is poorly understood. In this longitudinal study we used cluster analysis to explore acute stage individual profiles of injury age and cognition in 118 children with traumatic brain injury. Repeated measures of cognitive function were conducted at 30 months, indicating recovery, and 10 years post-injury, indicating development. Nine clusters were identified. Recovery was evident in three clusters, two of them with low functioning profiles. Developmental gains occurred for three clusters and an acute profile of higher freedom from distractibility (FFD) and lower processing speed (PS) was related to positive differences. One cluster, average low functioning and especially low verbal comprehension, demonstrated a slower development than peers. This suggests that developmental change after TBI in childhood takes place on a continuum, with both chance of long-term catching up, and risk of poor development. An acute profile of higher FFD and lower PS seemed to reflect injury consequences and were followed by developmental gains. These results challenge previous findings, and warrant further investigation.
KW - childhood
KW - cluster analysis
KW - cognition
KW - follow-up studies
KW - TBI
UR - http://www.scopus.com/inward/record.url?scp=84872141314&partnerID=8YFLogxK
U2 - 10.1089/neu.2012.2592
DO - 10.1089/neu.2012.2592
M3 - Article
C2 - 23025803
AN - SCOPUS:84872141314
SN - 0897-7151
VL - 30
SP - 76
EP - 83
JO - Journal of Neurotrauma
JF - Journal of Neurotrauma
IS - 2
ER -