TY - JOUR
T1 - Cognitive dysfunction in post-traumatic obsessivecompulsive disorder
AU - Borges, Manuela C.
AU - Braga, Daniela T.
AU - Igo, Sandro
AU - D'Alcante, Carina C.
AU - Sidrim, Ilduara
AU - MacHado, Maria Cristiana
AU - Pinto, Paula S.P.
AU - Cordioli, Aristides Volpato
AU - Do Rosrio, Maria Conceição
AU - Petrib, Ktia
AU - Mendlowicz, Mauro Vitor
AU - Mari, Jair de Jesus
AU - Miguel, Eurpedes C.
AU - Fontenelle, Leonardo F.
PY - 2011/1
Y1 - 2011/1
N2 - Objective: To investigate whether patients who develop obsessivecompulsive disorder (OCD) after posttraumatic stress disorder, i.e. post-traumatic OCD (PsT-OCD), display a distinctive neurocognitive pattern of dysfunction. Methods: Patients with PsT-OCD (n 16), pre-traumatic OCD (PrT-OCD) (n 18), non-traumatic OCD (NonT-OCD) (n 67) and healthy controls (n 17) had their performance compared on the following neuropsychological tests: the Wisconsin Card Sorting Test, the Iowa Gambling Task, the Wechsler Memory Scale Logical Memory, the Brief Visual Memory Test Revised, and the Wechsler Abbreviated Scale for Intelligence. Results: Patients with OCD, as a group, were characterized by poor set-shifting abilities and impaired verbal and visuospatial memories. Impaired set-shifting abilities were found to correlate with the severity of obsessivecompulsive symptoms in all groups of patients with OCD, with the exception of PsT-OCD. Only patients with PsT-OCD were characterized by impaired visuospatial recognition, which was found to correlate with poor set-shifting abilities in this particular group of patients, but not in individuals with other types of OCD or in healthy controls. Conclusions: Our study suggests that PsT-OCD is associated with a distinctive pattern of neurocognitive dysfunction, thus providing support for a different subtype of OCD.
AB - Objective: To investigate whether patients who develop obsessivecompulsive disorder (OCD) after posttraumatic stress disorder, i.e. post-traumatic OCD (PsT-OCD), display a distinctive neurocognitive pattern of dysfunction. Methods: Patients with PsT-OCD (n 16), pre-traumatic OCD (PrT-OCD) (n 18), non-traumatic OCD (NonT-OCD) (n 67) and healthy controls (n 17) had their performance compared on the following neuropsychological tests: the Wisconsin Card Sorting Test, the Iowa Gambling Task, the Wechsler Memory Scale Logical Memory, the Brief Visual Memory Test Revised, and the Wechsler Abbreviated Scale for Intelligence. Results: Patients with OCD, as a group, were characterized by poor set-shifting abilities and impaired verbal and visuospatial memories. Impaired set-shifting abilities were found to correlate with the severity of obsessivecompulsive symptoms in all groups of patients with OCD, with the exception of PsT-OCD. Only patients with PsT-OCD were characterized by impaired visuospatial recognition, which was found to correlate with poor set-shifting abilities in this particular group of patients, but not in individuals with other types of OCD or in healthy controls. Conclusions: Our study suggests that PsT-OCD is associated with a distinctive pattern of neurocognitive dysfunction, thus providing support for a different subtype of OCD.
KW - Neuropsychiatry
KW - Obsessivecompulsive disorder
KW - Post-traumatic stress disorder
KW - Trauma
UR - http://www.scopus.com/inward/record.url?scp=78650652824&partnerID=8YFLogxK
U2 - 10.3109/00048674.2010.527822
DO - 10.3109/00048674.2010.527822
M3 - Article
AN - SCOPUS:78650652824
SN - 0004-8674
VL - 45
SP - 76
EP - 85
JO - Australian and New Zealand Journal of Psychiatry
JF - Australian and New Zealand Journal of Psychiatry
IS - 1
ER -