Cognitive dysfunction in post-traumatic obsessivecompulsive disorder

Manuela C. Borges, Daniela T. Braga, Sandro Igo, Carina C. D'Alcante, Ilduara Sidrim, Maria Cristiana MacHado, Paula S.P. Pinto, Aristides Volpato Cordioli, Maria Conceição Do Rosrio, Ktia Petrib, Mauro Vitor Mendlowicz, Jair de Jesus Mari, Eurpedes C. Miguel, Leonardo F. Fontenelle

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6 Citations (Scopus)


Objective: To investigate whether patients who develop obsessivecompulsive disorder (OCD) after posttraumatic stress disorder, i.e. post-traumatic OCD (PsT-OCD), display a distinctive neurocognitive pattern of dysfunction. Methods: Patients with PsT-OCD (n 16), pre-traumatic OCD (PrT-OCD) (n 18), non-traumatic OCD (NonT-OCD) (n 67) and healthy controls (n 17) had their performance compared on the following neuropsychological tests: the Wisconsin Card Sorting Test, the Iowa Gambling Task, the Wechsler Memory Scale Logical Memory, the Brief Visual Memory Test Revised, and the Wechsler Abbreviated Scale for Intelligence. Results: Patients with OCD, as a group, were characterized by poor set-shifting abilities and impaired verbal and visuospatial memories. Impaired set-shifting abilities were found to correlate with the severity of obsessivecompulsive symptoms in all groups of patients with OCD, with the exception of PsT-OCD. Only patients with PsT-OCD were characterized by impaired visuospatial recognition, which was found to correlate with poor set-shifting abilities in this particular group of patients, but not in individuals with other types of OCD or in healthy controls. Conclusions: Our study suggests that PsT-OCD is associated with a distinctive pattern of neurocognitive dysfunction, thus providing support for a different subtype of OCD.

Original languageEnglish
Pages (from-to)76-85
Number of pages10
JournalAustralian & New Zealand Journal of Psychiatry
Issue number1
Publication statusPublished - Jan 2011
Externally publishedYes


  • Neuropsychiatry
  • Obsessivecompulsive disorder
  • Post-traumatic stress disorder
  • Trauma

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