Coding GPCR-G protein specificity

Sebastian G.B. Furness; Patrick M. Sexton

doi:10.1038/cr.2017.92

Coding GPCR-G protein specificity

Sebastian G.B. Furness, Patrick M. Sexton

Research output: Contribution to journal › Short Survey › Research › peer-review

1 Citation (Scopus)

Abstract

G protein-coupled receptors (GPCRs) are ubiquitous gatekeepers of cellular response and signal predominantly by recruitment and activation of G proteins. In a recent paper in Nature, Flock et al. use large-scale bioinformatics to build a model of GPCR-G protein selectivity and an interactive database to interrogate potential receptor-G protein interactions.

Original language	English
Pages (from-to)	1193-1194
Number of pages	2
Journal	Cell Research
Volume	27
Issue number	10
DOIs	https://doi.org/10.1038/cr.2017.92
Publication status	Published - 1 Oct 2017

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Cite this

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title = "Coding GPCR-G protein specificity",

abstract = "G protein-coupled receptors (GPCRs) are ubiquitous gatekeepers of cellular response and signal predominantly by recruitment and activation of G proteins. In a recent paper in Nature, Flock et al. use large-scale bioinformatics to build a model of GPCR-G protein selectivity and an interactive database to interrogate potential receptor-G protein interactions.",

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