Coding GPCR-G protein specificity

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G protein-coupled receptors (GPCRs) are ubiquitous gatekeepers of cellular response and signal predominantly by recruitment and activation of G proteins. In a recent paper in Nature, Flock et al. use large-scale bioinformatics to build a model of GPCR-G protein selectivity and an interactive database to interrogate potential receptor-G protein interactions.
Original languageEnglish
Pages (from-to)1193-1194
Number of pages2
JournalCell Research
Issue number10
Publication statusPublished - 1 Oct 2017

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