Cobb syndrome: a case report and systematic review of the literature

Marissa Tubridy Clark, Emma L Brooks, Winston Chong, Chris Pappas, Michael Collingwood Fahey

Research output: Contribution to journalArticleOther

Abstract

We report on a case of Cobb syndrome, a rare metameric disorder, characterized by a vascular abnormality of the spinal cord, with an associated vascular skin lesion of the same metamere, in an 8-year-old girl presenting with leg weakness. Magnetic resonance imaging revealed a spinal arteriovenous malformation at the level of T10-L5. This finding, together with a large, pigmented nevus at this level, is diagnostic for Cobb syndrome. A systematic review of the literature on Cobb syndrome, with a focus on treatment and outcomes, is presented. Current treatment options include combinations of embolization, neurosurgical intervention, corticosteroid therapy, and radiotherapy.
Original languageEnglish
Pages (from-to)423 - 425
Number of pages3
JournalPediatric Neurology
Volume39
Issue number6
Publication statusPublished - 2008

Cite this

Clark, Marissa Tubridy ; Brooks, Emma L ; Chong, Winston ; Pappas, Chris ; Fahey, Michael Collingwood. / Cobb syndrome: a case report and systematic review of the literature. In: Pediatric Neurology. 2008 ; Vol. 39, No. 6. pp. 423 - 425.
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Clark, MT, Brooks, EL, Chong, W, Pappas, C & Fahey, MC 2008, 'Cobb syndrome: a case report and systematic review of the literature' Pediatric Neurology, vol. 39, no. 6, pp. 423 - 425.

Cobb syndrome: a case report and systematic review of the literature. / Clark, Marissa Tubridy; Brooks, Emma L; Chong, Winston; Pappas, Chris; Fahey, Michael Collingwood.

In: Pediatric Neurology, Vol. 39, No. 6, 2008, p. 423 - 425.

Research output: Contribution to journalArticleOther

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T1 - Cobb syndrome: a case report and systematic review of the literature

AU - Clark, Marissa Tubridy

AU - Brooks, Emma L

AU - Chong, Winston

AU - Pappas, Chris

AU - Fahey, Michael Collingwood

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