Clonal relationship among invasive and non-invasive strains of enteroinvasive Escherichia coli serogroups

Marina Martinez; Thomas Whittan; Elizabeth McGraw; Josias Rodrigues; Luiz Trabulsi

doi:10.1111/j.1574-6968.1999.tb13462.x

Clonal relationship among invasive and non-invasive strains of enteroinvasive Escherichia coli serogroups

Marina Martinez, Thomas Whittan, Elizabeth McGraw, Josias Rodrigues, Luiz Trabulsi

Research output: Contribution to journal › Article › Research › peer-review

17 Citations (Scopus)

Abstract

The genetic relatedness among 96 invasive Escherichia coli belonging to several serogroups and 13 non-invasive of several serotypes that share the same O antigen was investigated by multilocus enzyme electrophoresis analysis. The invasive strains were isolated in different parts of the world and most of them recovered from dysentery. Twenty-nine electrophoretic types were distinguished and the most invasive strains were found to belong to two major lineages. These results suggested that the invasive ability in these strains has evolved in divergent chromosomal backgrounds, presumably through the horizontal spread of plasmid-borne invasion genes. The maintenance of invasive phenotypes in separate lineages suggests that this ability confers a selective advantage to invasive strains.

Original language	English
Pages (from-to)	145 - 151
Number of pages	7
Journal	FEMS Microbiology Letters
Volume	172
Issue number	2
DOIs	https://doi.org/10.1111/j.1574-6968.1999.tb13462.x
Publication status	Published - 1999
Externally published	Yes

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10.1111/j.1574-6968.1999.tb13462.x

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title = "Clonal relationship among invasive and non-invasive strains of enteroinvasive Escherichia coli serogroups",

abstract = "The genetic relatedness among 96 invasive Escherichia coli belonging to several serogroups and 13 non-invasive of several serotypes that share the same O antigen was investigated by multilocus enzyme electrophoresis analysis. The invasive strains were isolated in different parts of the world and most of them recovered from dysentery. Twenty-nine electrophoretic types were distinguished and the most invasive strains were found to belong to two major lineages. These results suggested that the invasive ability in these strains has evolved in divergent chromosomal backgrounds, presumably through the horizontal spread of plasmid-borne invasion genes. The maintenance of invasive phenotypes in separate lineages suggests that this ability confers a selective advantage to invasive strains.",

author = "Marina Martinez and Thomas Whittan and Elizabeth McGraw and Josias Rodrigues and Luiz Trabulsi",

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doi = "10.1111/j.1574-6968.1999.tb13462.x",

language = "English",

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pages = "145 -- 151",

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T1 - Clonal relationship among invasive and non-invasive strains of enteroinvasive Escherichia coli serogroups

AU - Martinez, Marina

AU - Whittan, Thomas

AU - McGraw, Elizabeth

AU - Rodrigues, Josias

AU - Trabulsi, Luiz

PY - 1999

Y1 - 1999

N2 - The genetic relatedness among 96 invasive Escherichia coli belonging to several serogroups and 13 non-invasive of several serotypes that share the same O antigen was investigated by multilocus enzyme electrophoresis analysis. The invasive strains were isolated in different parts of the world and most of them recovered from dysentery. Twenty-nine electrophoretic types were distinguished and the most invasive strains were found to belong to two major lineages. These results suggested that the invasive ability in these strains has evolved in divergent chromosomal backgrounds, presumably through the horizontal spread of plasmid-borne invasion genes. The maintenance of invasive phenotypes in separate lineages suggests that this ability confers a selective advantage to invasive strains.

AB - The genetic relatedness among 96 invasive Escherichia coli belonging to several serogroups and 13 non-invasive of several serotypes that share the same O antigen was investigated by multilocus enzyme electrophoresis analysis. The invasive strains were isolated in different parts of the world and most of them recovered from dysentery. Twenty-nine electrophoretic types were distinguished and the most invasive strains were found to belong to two major lineages. These results suggested that the invasive ability in these strains has evolved in divergent chromosomal backgrounds, presumably through the horizontal spread of plasmid-borne invasion genes. The maintenance of invasive phenotypes in separate lineages suggests that this ability confers a selective advantage to invasive strains.

UR - http://onlinelibrary.wiley.com/doi/10.1111/j.1574-6968.1999.tb13462.x/pdf

U2 - 10.1111/j.1574-6968.1999.tb13462.x

DO - 10.1111/j.1574-6968.1999.tb13462.x

M3 - Article

VL - 172

SP - 145

EP - 151

JO - FEMS Microbiology Letters

JF - FEMS Microbiology Letters

SN - 0378-1097

IS - 2

ER -

Clonal relationship among invasive and non-invasive strains of enteroinvasive Escherichia coli serogroups

Abstract

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