Clinical trial: effects of adefovir dipivoxil therapy in Asian and Caucasian patients with chronic hepatitis B

S G Lim; Patrick Marcellin; N Tassopoulos; S Hadziyannis; T Chang; T Tong; William Sievert; P Hu; Sarah Arterburn; Carol L Brosgart

doi:10.1111/j.1365-2036.2007.03506.x

Clinical trial: effects of adefovir dipivoxil therapy in Asian and Caucasian patients with chronic hepatitis B

S G Lim, Patrick Marcellin, N Tassopoulos, S Hadziyannis, T Chang, T Tong, William Sievert, P Hu, Sarah Arterburn, Carol L Brosgart

Medicine Monash Health

Research output: Contribution to journal › Article › Research › peer-review

23 Citations (Scopus)

Abstract

Background Two-thirds of the 350 million people infected with chronic hepatitis B virus live in the Asia-Pacific region. Aim To compare the effects of adefovir dipivoxil therapy between Asian and Caucasian patients with chronic hepatitis B. Methods The safety and efficacy of 10 mg of adefovir dipivoxil was compared to placebo in 501 Asian (n = 259) or Caucasian (n = 242) HBeAg+ and HBeAg) chronic hepatitis B virus patients treated for 48 weeks in two randomized, double-blind, placebo-controlled studies.

Original language	English
Pages (from-to)	1419 - 1428
Number of pages	10
Journal	Alimentary Pharmacology & Therapeutics
Volume	26
Issue number	10
DOIs	https://doi.org/10.1111/j.1365-2036.2007.03506.x
Publication status	Published - 2007

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abstract = "Background Two-thirds of the 350 million people infected with chronic hepatitis B virus live in the Asia-Pacific region. Aim To compare the effects of adefovir dipivoxil therapy between Asian and Caucasian patients with chronic hepatitis B. Methods The safety and efficacy of 10 mg of adefovir dipivoxil was compared to placebo in 501 Asian (n = 259) or Caucasian (n = 242) HBeAg+ and HBeAg) chronic hepatitis B virus patients treated for 48 weeks in two randomized, double-blind, placebo-controlled studies.",

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T1 - Clinical trial: effects of adefovir dipivoxil therapy in Asian and Caucasian patients with chronic hepatitis B

AU - Lim, S G

AU - Marcellin, Patrick

AU - Tassopoulos, N

AU - Hadziyannis, S

AU - Chang, T

AU - Tong, T

AU - Sievert, William

AU - Hu, P

AU - Arterburn, Sarah

AU - Brosgart, Carol L

PY - 2007

Y1 - 2007

N2 - Background Two-thirds of the 350 million people infected with chronic hepatitis B virus live in the Asia-Pacific region. Aim To compare the effects of adefovir dipivoxil therapy between Asian and Caucasian patients with chronic hepatitis B. Methods The safety and efficacy of 10 mg of adefovir dipivoxil was compared to placebo in 501 Asian (n = 259) or Caucasian (n = 242) HBeAg+ and HBeAg) chronic hepatitis B virus patients treated for 48 weeks in two randomized, double-blind, placebo-controlled studies.

AB - Background Two-thirds of the 350 million people infected with chronic hepatitis B virus live in the Asia-Pacific region. Aim To compare the effects of adefovir dipivoxil therapy between Asian and Caucasian patients with chronic hepatitis B. Methods The safety and efficacy of 10 mg of adefovir dipivoxil was compared to placebo in 501 Asian (n = 259) or Caucasian (n = 242) HBeAg+ and HBeAg) chronic hepatitis B virus patients treated for 48 weeks in two randomized, double-blind, placebo-controlled studies.

UR - http://www3.interscience.wiley.com.ezproxy.lib.monash.edu.au/cgi-bin/fulltext/117987767/PDFSTART

U2 - 10.1111/j.1365-2036.2007.03506.x

DO - 10.1111/j.1365-2036.2007.03506.x

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EP - 1428

JO - Alimentary Pharmacology & Therapeutics

JF - Alimentary Pharmacology & Therapeutics

SN - 0269-2813

IS - 10

ER -

Clinical trial: effects of adefovir dipivoxil therapy in Asian and Caucasian patients with chronic hepatitis B

Abstract

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