Clinical, microbiological, and economic benefit of a change in antibiotic prophylaxis for cardiac surgery

Denis Spelman; Glenys Harrington; Phil Russo; S. Wesselingh

doi:10.1086/502074

Clinical, microbiological, and economic benefit of a change in antibiotic prophylaxis for cardiac surgery

Denis Spelman
, Glenys Harrington
, Phil Russo
, S. Wesselingh

Research output: Contribution to journal › Article › Research › peer-review

39 Citations (Scopus)

Abstract

Vancomycin and rifampicin replaced cephazolin as antibiotic prophylaxis for coronary artery bypass surgery at our institution. Following this intervention, there was a significant decrease (P < .001) in the surgical-site infection rate from 10.5 (95% confidence interval, 8.2 to 13.3) to 4.9 (95% confidence interval, 3.2 to 7.1) infections per 100 procedures. An estimated $576,655 (Australian) was saved between two 12-month periods.

Original language	English
Pages (from-to)	402-404
Number of pages	3
Journal	Infection Control & Hospital Epidemiology
Volume	23
Issue number	7
DOIs	https://doi.org/10.1086/502074
Publication status	Published - 1 Jan 2002

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SDG 3 Good Health and Well-being

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10.1086/502074

Cite this

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abstract = "Vancomycin and rifampicin replaced cephazolin as antibiotic prophylaxis for coronary artery bypass surgery at our institution. Following this intervention, there was a significant decrease (P < .001) in the surgical-site infection rate from 10.5 (95\% confidence interval, 8.2 to 13.3) to 4.9 (95\% confidence interval, 3.2 to 7.1) infections per 100 procedures. An estimated \$576,655 (Australian) was saved between two 12-month periods.",

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AB - Vancomycin and rifampicin replaced cephazolin as antibiotic prophylaxis for coronary artery bypass surgery at our institution. Following this intervention, there was a significant decrease (P < .001) in the surgical-site infection rate from 10.5 (95% confidence interval, 8.2 to 13.3) to 4.9 (95% confidence interval, 3.2 to 7.1) infections per 100 procedures. An estimated $576,655 (Australian) was saved between two 12-month periods.

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Clinical, microbiological, and economic benefit of a change in antibiotic prophylaxis for cardiac surgery

Abstract

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