Clinical, microbiological, and economic benefit of a change in antibiotic prophylaxis for cardiac surgery

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34 Citations (Scopus)

Abstract

Vancomycin and rifampicin replaced cephazolin as antibiotic prophylaxis for coronary artery bypass surgery at our institution. Following this intervention, there was a significant decrease (P < .001) in the surgical-site infection rate from 10.5 (95% confidence interval, 8.2 to 13.3) to 4.9 (95% confidence interval, 3.2 to 7.1) infections per 100 procedures. An estimated $576,655 (Australian) was saved between two 12-month periods.

Original languageEnglish
Pages (from-to)402-404
Number of pages3
JournalInfection Control and Hospital Epidemiology
Volume23
Issue number7
DOIs
Publication statusPublished - 1 Jan 2002

Cite this

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Clinical, microbiological, and economic benefit of a change in antibiotic prophylaxis for cardiac surgery. / Spelman, Denis; Harrington, Glenys; Russo, Phil; Wesselingh, S.

In: Infection Control and Hospital Epidemiology, Vol. 23, No. 7, 01.01.2002, p. 402-404.

Research output: Contribution to journalArticleResearchpeer-review

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