Clinical, microbiological, and economic benefit of a change in antibiotic prophylaxis for cardiac surgery

Denis Spelman; Glenys Harrington; Phil Russo; S. Wesselingh

doi:10.1086/502074

Clinical, microbiological, and economic benefit of a change in antibiotic prophylaxis for cardiac surgery

Denis Spelman, Glenys Harrington, Phil Russo, S. Wesselingh

Research output: Contribution to journal › Article › Research › peer-review

38 Citations (Scopus)

Abstract

Vancomycin and rifampicin replaced cephazolin as antibiotic prophylaxis for coronary artery bypass surgery at our institution. Following this intervention, there was a significant decrease (P < .001) in the surgical-site infection rate from 10.5 (95% confidence interval, 8.2 to 13.3) to 4.9 (95% confidence interval, 3.2 to 7.1) infections per 100 procedures. An estimated $576,655 (Australian) was saved between two 12-month periods.

Original language	English
Pages (from-to)	402-404
Number of pages	3
Journal	Infection Control & Hospital Epidemiology
Volume	23
Issue number	7
DOIs	https://doi.org/10.1086/502074
Publication status	Published - 1 Jan 2002

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1086/502074

Cite this

@article{f4aacc3b2ee643fcba7177ae66cfc901,

title = "Clinical, microbiological, and economic benefit of a change in antibiotic prophylaxis for cardiac surgery",

abstract = "Vancomycin and rifampicin replaced cephazolin as antibiotic prophylaxis for coronary artery bypass surgery at our institution. Following this intervention, there was a significant decrease (P < .001) in the surgical-site infection rate from 10.5 (95% confidence interval, 8.2 to 13.3) to 4.9 (95% confidence interval, 3.2 to 7.1) infections per 100 procedures. An estimated $576,655 (Australian) was saved between two 12-month periods.",

author = "Denis Spelman and Glenys Harrington and Phil Russo and S. Wesselingh",

year = "2002",

month = jan,

day = "1",

doi = "10.1086/502074",

language = "English",

volume = "23",

pages = "402--404",

journal = "Infection Control & Hospital Epidemiology",

issn = "0899-823X",

publisher = "Cambridge University Press",

number = "7",

}

TY - JOUR

T1 - Clinical, microbiological, and economic benefit of a change in antibiotic prophylaxis for cardiac surgery

AU - Spelman, Denis

AU - Harrington, Glenys

AU - Russo, Phil

AU - Wesselingh, S.

PY - 2002/1/1

Y1 - 2002/1/1

N2 - Vancomycin and rifampicin replaced cephazolin as antibiotic prophylaxis for coronary artery bypass surgery at our institution. Following this intervention, there was a significant decrease (P < .001) in the surgical-site infection rate from 10.5 (95% confidence interval, 8.2 to 13.3) to 4.9 (95% confidence interval, 3.2 to 7.1) infections per 100 procedures. An estimated $576,655 (Australian) was saved between two 12-month periods.

AB - Vancomycin and rifampicin replaced cephazolin as antibiotic prophylaxis for coronary artery bypass surgery at our institution. Following this intervention, there was a significant decrease (P < .001) in the surgical-site infection rate from 10.5 (95% confidence interval, 8.2 to 13.3) to 4.9 (95% confidence interval, 3.2 to 7.1) infections per 100 procedures. An estimated $576,655 (Australian) was saved between two 12-month periods.

UR - http://www.scopus.com/inward/record.url?scp=0036328985&partnerID=8YFLogxK

U2 - 10.1086/502074

DO - 10.1086/502074

M3 - Article

C2 - 12138981

AN - SCOPUS:0036328985

VL - 23

SP - 402

EP - 404

JO - Infection Control & Hospital Epidemiology

JF - Infection Control & Hospital Epidemiology

SN - 0899-823X

IS - 7

ER -

Clinical, microbiological, and economic benefit of a change in antibiotic prophylaxis for cardiac surgery

Abstract

UN SDGs

Access to Document

Other files and links

Cite this