"Clicking" polymers or just efficient linking: What is the difference?

Christopher Barner-Kowollik, Filip E. Du Prez, Pieter Espeel, Craig J. Hawker, Thomas Junkers, Helmut Schlaad, Wim Van Camp

Research output: Contribution to journalArticleOtherpeer-review

508 Citations (Scopus)


The "click" trick: Many reactions are classified as click reactions even though some are limited to certain applications. Thus, there is danger that the term "click" will become meaningless over time and simply a synonym for "successful". To prevent this, the original click criteria are evaluated in this Essay specifically for the synthetic polymer field and a set of criteria are specified that distinguishes click from other efficient reactions.

Original languageEnglish
Pages (from-to)60-62
Number of pages3
JournalAngewandte Chemie - International Edition
Issue number1
Publication statusPublished - 3 Jan 2011
Externally publishedYes


  • click reactions
  • polymer chemistry
  • polymer conjugation
  • selectivity

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