Clicking dendritic peptides onto single walled carbon nanotubes

Eli Moore; Peng Yuan Wang; Andrew P. Vogt; Christopher T. Gibson; Vattekat Haridas; Nicolas H. Voelcker

doi:10.1039/c2ra00791f

Clicking dendritic peptides onto single walled carbon nanotubes

Eli Moore, Peng Yuan Wang, Andrew P. Vogt, Christopher T. Gibson, Vattekat Haridas, Nicolas H. Voelcker

Research output: Contribution to journal › Article › Research › peer-review

12 Citations (Scopus)

Abstract

Here, we demonstrate a straightforward click-chemistry-based approach for the functionalisation of single walled carbon nanotubes with oligo-lysine dendrons. Azide-functionalised nanotubes were reacted with alkyne-focal dendrons using the 1,3 dipolar Cu-catalysed azide alkyne cycloaddition reaction. Peptide dendron functionalised nanotubes showed significantly increased biocompatibility in rat mesenchymal stem cell culture.

Original language	English
Pages (from-to)	1289-1291
Number of pages	3
Journal	RSC Advances
Volume	2
Issue number	4
DOIs	https://doi.org/10.1039/c2ra00791f
Publication status	Published - 21 Feb 2012
Externally published	Yes

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10.1039/c2ra00791f

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abstract = "Here, we demonstrate a straightforward click-chemistry-based approach for the functionalisation of single walled carbon nanotubes with oligo-lysine dendrons. Azide-functionalised nanotubes were reacted with alkyne-focal dendrons using the 1,3 dipolar Cu-catalysed azide alkyne cycloaddition reaction. Peptide dendron functionalised nanotubes showed significantly increased biocompatibility in rat mesenchymal stem cell culture. ",

author = "Eli Moore and Wang, \{Peng Yuan\} and Vogt, \{Andrew P.\} and Gibson, \{Christopher T.\} and Vattekat Haridas and Voelcker, \{Nicolas H.\}",

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AU - Moore, Eli

AU - Wang, Peng Yuan

AU - Vogt, Andrew P.

AU - Gibson, Christopher T.

AU - Haridas, Vattekat

AU - Voelcker, Nicolas H.

PY - 2012/2/21

Y1 - 2012/2/21

N2 - Here, we demonstrate a straightforward click-chemistry-based approach for the functionalisation of single walled carbon nanotubes with oligo-lysine dendrons. Azide-functionalised nanotubes were reacted with alkyne-focal dendrons using the 1,3 dipolar Cu-catalysed azide alkyne cycloaddition reaction. Peptide dendron functionalised nanotubes showed significantly increased biocompatibility in rat mesenchymal stem cell culture.

AB - Here, we demonstrate a straightforward click-chemistry-based approach for the functionalisation of single walled carbon nanotubes with oligo-lysine dendrons. Azide-functionalised nanotubes were reacted with alkyne-focal dendrons using the 1,3 dipolar Cu-catalysed azide alkyne cycloaddition reaction. Peptide dendron functionalised nanotubes showed significantly increased biocompatibility in rat mesenchymal stem cell culture.

UR - https://www.scopus.com/pages/publications/84859151183

U2 - 10.1039/c2ra00791f

DO - 10.1039/c2ra00791f

M3 - Article

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Clicking dendritic peptides onto single walled carbon nanotubes

Abstract

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