Click-engineered, bioresponsive, drug-loaded PEG spheres

Heng Pho Yap, Angus P R Johnston, Georgina Kate Such, Yan Yan, Frank Caruso

Research output: Contribution to journalArticleResearchpeer-review

27 Citations (Scopus)

Abstract

A click-chemistry approach to synthesize bioresponsive poly(ethylene glycol acrylate) particles is described. The particles are loaded with a model anticancer drug (doxorubicin, DOX), and undergo simultaneous particle deconstruction and DOX release upon specific activation by the simulated environment of the cellular cytoplasm.

Original languageEnglish
Pages (from-to)4348-4352
Number of pages5
JournalAdvanced Materials
Volume21
Issue number43
DOIs
Publication statusPublished - 20 Nov 2009
Externally publishedYes

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