Abstract
| Original language | English |
|---|---|
| Pages (from-to) | 1210 - 1217 |
| Number of pages | 8 |
| Journal | Inflammatory Bowel Diseases |
| Volume | 19 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - 2013 |
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Chronic pain in inflammatory bowel disease: characteristics and associations of a hospital-based cohort. / Morrison, Graham; van Langenberg, Daniel; Gibson, Stephen; Gibson, Peter Raymond.
In: Inflammatory Bowel Diseases, Vol. 19, No. 6, 2013, p. 1210 - 1217.Research output: Contribution to journal › Article › Research › peer-review
TY - JOUR
T1 - Chronic pain in inflammatory bowel disease: characteristics and associations of a hospital-based cohort
AU - Morrison, Graham
AU - van Langenberg, Daniel
AU - Gibson, Stephen
AU - Gibson, Peter Raymond
PY - 2013
Y1 - 2013
N2 - ackground: Chronic pain (CP) is a common symptom in patients with inflammatory bowel disease. This study aimed to examine its prevalence, severity, clinical associations, and impact on psychological well-being and to identify patient factors that independently predict the presence of severe/disabling pain. Methods: One hundred and twenty consecutive patients with inflammatory bowel disease attending a hospital-based clinic provided information through questionnaires on quality of life, mood disturbance, and functional gut symptoms. Those who had CP (pain occurring every day for 3 months within the past 6 months) provided additional information on the pain s intensity and associated disability and management and coping strategies. Results: Forty-six patients (38 ) had CP, most commonly in the abdomen (91 ), and they had higher disease activity, reduced quality of life, and more depression and anxiety and took more paracetamol and opiates than those without. These indices were worse in the subgroup of 23 with moderate-severe pain/disability. Criteria for irritable bowel syndrome were met in 70 of those with pain irrespective of its severity. Multivariate analysis identified 4 independent associations with moderate-severe pain/disability: active disease (odds ratio, 49 [95 confidence intervals, 1.6-1455]), catastrophizing tendency (35 [3-228]), medication belief score (0.05 [0.005-0.55], and depression score (1.80 [1.02-3.17]). Conclusions: CP has major effects on quality of life and functional and social outcomes. Active disease and maladaptive coping strategies and negative attitudes and beliefs toward symptoms are independently associated with more severe pain. Management strategies should move the focus away from analgesic dependence toward psychosocial intervention and nonpharmacologic therapy
AB - ackground: Chronic pain (CP) is a common symptom in patients with inflammatory bowel disease. This study aimed to examine its prevalence, severity, clinical associations, and impact on psychological well-being and to identify patient factors that independently predict the presence of severe/disabling pain. Methods: One hundred and twenty consecutive patients with inflammatory bowel disease attending a hospital-based clinic provided information through questionnaires on quality of life, mood disturbance, and functional gut symptoms. Those who had CP (pain occurring every day for 3 months within the past 6 months) provided additional information on the pain s intensity and associated disability and management and coping strategies. Results: Forty-six patients (38 ) had CP, most commonly in the abdomen (91 ), and they had higher disease activity, reduced quality of life, and more depression and anxiety and took more paracetamol and opiates than those without. These indices were worse in the subgroup of 23 with moderate-severe pain/disability. Criteria for irritable bowel syndrome were met in 70 of those with pain irrespective of its severity. Multivariate analysis identified 4 independent associations with moderate-severe pain/disability: active disease (odds ratio, 49 [95 confidence intervals, 1.6-1455]), catastrophizing tendency (35 [3-228]), medication belief score (0.05 [0.005-0.55], and depression score (1.80 [1.02-3.17]). Conclusions: CP has major effects on quality of life and functional and social outcomes. Active disease and maladaptive coping strategies and negative attitudes and beliefs toward symptoms are independently associated with more severe pain. Management strategies should move the focus away from analgesic dependence toward psychosocial intervention and nonpharmacologic therapy
UR - http://www.ncbi.nlm.nih.gov/pubmed/23524595
U2 - 10.1097/MIB.0b013e318280e729
DO - 10.1097/MIB.0b013e318280e729
M3 - Article
VL - 19
SP - 1210
EP - 1217
JO - Inflammatory Bowel Diseases
JF - Inflammatory Bowel Diseases
SN - 1078-0998
IS - 6
ER -