Cholesterol - A biological compound as a building block in bionanotechnology

Leticia Hosta-Rigau, Yan Zhang, Boon M. Teo, Almar Postma, Brigitte Städler

Research output: Contribution to journalArticleResearchpeer-review

72 Citations (Scopus)

Abstract

Cholesterol is a molecule with many tasks in nature but also a long history in science. This feature article highlights the contribution of this small compound to bionanotechnology. We discuss relevant chemical aspects in this context followed by an overview of its self-assembly capabilities both as a free molecule and when conjugated to a polymer. Further, cholesterol in the context of liposomes is reviewed and its impact ranging from biosensing to drug delivery is outlined. Cholesterol is and will be an indispensable player in bionanotechnology, contributing to the progress of this potent field of research.

Original languageEnglish
Pages (from-to)89-109
Number of pages21
JournalNanoscale
Volume5
Issue number1
DOIs
Publication statusPublished - 7 Jan 2013
Externally publishedYes

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