Cholecalciferol supplementation throughout winter does not affect markers of bone turnover in healthy young and elderly adults

Kelly Seamans, Tom Hill, Julie Wallace, Geraldine Horigan, Alice Lucey, Maria Barnes, Nicola Taylor, Maxine Bonham, Siobhan Muldowney, Emeir Duffy, Sean J J Strain, Mairead Kiely, Kevin Cashman

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25 Citations (Scopus)

Abstract

Although there have been several studies of the effect of vitamin D status on bone turnover in the elderly, the findings are unclear, and, furthermore, to date very few have investigated this in young adults. The objective of these randomized, placebo-controlled, double-blind, 2-center intervention studies was to investigate the effect of cholecalciferol supplementation (0, 5, 10, and 15 microg cholecalciferol/d) throughout winter time on indices of vitamin D status and bone turnover in young (aged 20-40 y; n = 215) and elderly (aged > or = 64 y; n = 204) adults, with relatively high mean calcium intakes of 976 and 874 mg/d, respectively.
Original languageEnglish
Pages (from-to)454 - 460
Number of pages7
JournalThe Journal of Nutrition
Volume140
Issue number3
DOIs
Publication statusPublished - 2010

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