TY - JOUR
T1 - Cholecalciferol supplementation throughout winter does not affect markers of bone turnover in healthy young and elderly adults
AU - Seamans, Kelly
AU - Hill, Tom
AU - Wallace, Julie
AU - Horigan, Geraldine
AU - Lucey, Alice
AU - Barnes, Maria
AU - Taylor, Nicola
AU - Bonham, Maxine
AU - Muldowney, Siobhan
AU - Duffy, Emeir
AU - Strain, Sean J J
AU - Kiely, Mairead
AU - Cashman, Kevin
PY - 2010
Y1 - 2010
N2 - Although there have been several studies of the effect of vitamin D status on bone turnover in the elderly, the findings are unclear, and, furthermore, to date very few have investigated this in young adults. The objective of these randomized, placebo-controlled, double-blind, 2-center intervention studies was to investigate the effect of cholecalciferol supplementation (0, 5, 10, and 15 microg cholecalciferol/d) throughout winter time on indices of vitamin D status and bone turnover in young (aged 20-40 y; n = 215) and elderly (aged > or = 64 y; n = 204) adults, with relatively high mean calcium intakes of 976 and 874 mg/d, respectively.
AB - Although there have been several studies of the effect of vitamin D status on bone turnover in the elderly, the findings are unclear, and, furthermore, to date very few have investigated this in young adults. The objective of these randomized, placebo-controlled, double-blind, 2-center intervention studies was to investigate the effect of cholecalciferol supplementation (0, 5, 10, and 15 microg cholecalciferol/d) throughout winter time on indices of vitamin D status and bone turnover in young (aged 20-40 y; n = 215) and elderly (aged > or = 64 y; n = 204) adults, with relatively high mean calcium intakes of 976 and 874 mg/d, respectively.
UR - http://jn.nutrition.org/content/140/3/454.full.pdf+html
U2 - 10.3945/jn.109.113480
DO - 10.3945/jn.109.113480
M3 - Article
SN - 0022-3166
VL - 140
SP - 454
EP - 460
JO - The Journal of Nutrition
JF - The Journal of Nutrition
IS - 3
ER -